BACKGROUND There is a dire need for the discovery and development of new antimicrobial agents after several experiments for a better resistance of microorganisms towards antimicrobial agents become a serious health problem for a few years in the past. As benzimidazole possess various types of biological activities, it has been synthesized, in the present study, a new series of (5-(3-(1H-benzo[d...

In the title complex, [Zn(C(4)H(3)N(6))(2)(H(2)O)(2)], the metal centre lies on an inversion centre and displays a distorted octa-hedral ZnN(4)O(2) coordination geometry. The organic ligand is not planar; the dihedral angle between the imidazole and tetra-zole rings is 8.39 (9)°. An extended network of inter-molecular N-H⋯N and O-H⋯N hydrogen bonds stabilizes the crystal structure.

Stable crystalline phosphorus ylides are obtained in excellent yields from the 1:1:1 addition reactionbetween hydantoins or thiohydantoins and dialkyl acetylenedicarboxylates in the presence oftriphenylphosphine. These phosphoranes undergo smooth intramolecular Wittig reaction followedby an electrocyclic ring opening to produce dialkyl (E)-2-(2,5-dihydro-5,5-diaryl-2-thioxo-1H-imidazol-4-yl)fum...

Three types of per-O-methylated β-cyclodextrin dimers, Im2CD, Im3NHCD and Py3NHCD, were prepared as globin models. Im2CD was synthesized by the condensation reaction of mono(2(A)-amino)-per-O-methylated β-cyclodextrin with 3-(1H-imidazol-1-yl)pentanedioic acid. Im3NHCD and Py3NHCD were obtained through the S(N)2 reactions of mono(2(A),3(A)-epoxy)-per-O-methylated β-cyclodextrin with 3-(1H-imida...