How has the Atlantic Meridional Overturning Circulation (AMOC) varied over the past centuries and what is the risk of an anthropogenic AMOC collapse? Current AMOC projections have broken important new ground, but either use only a small subset of the relevant observational constraints or sample mostly in the region around the best parameter estimates. Here we improve on previous studies by (i) ...

Introduction The use of contraception among currently married women in India has increased from 41 percent in 1992-93 to 56 percent in 2005-06, while the use of spacing method increased slowly; from 10 percent to 18 percent in the same period (IIPS and Macro International, 1995, 2000, and 2007). On the contrary about 27 percent of users of all methods in the country discontinued use within 12 m...

BACKGROUND AND PURPOSE Many cases of subarachnoid hemorrhage are due to rupture of small cerebral aneurysms. Our purpose was to evaluate the usefulness of helical CT angiography (CTA) in the detection and characterization of very small (<5 mm) intracranial aneurysms. METHODS One hundred eighty consecutive patients underwent CTA for suspected intracranial aneurysms. All aneurysms prospectively...

The characteristics and extent of rapid or acute resetting of the aortic baroreceptors were studied in long-term renal hypertensive rats during 30 minutes of sustained hypertension produced by phenylephrine infusion. The aortic baroreceptors of hypertensive rats exhibited complete resetting to hypertension because during the control period the systolic threshold pressure for activation of the b...

While the outcome of in-hospital cardiopulmonary arrest has been studied extensively, the clinical antecedents of arrest are less well defined. We studied a group of consecutive general hospital ward patients developing cardiopulmonary arrest. Prospectively determined definitions of underlying pathophysiology, severity of underlying disease, patient complaints, and clinical observations were us...

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Current researches have showed that N3, N5-diaryl-2, 6-dimethyl -1, 4-dihydropyrine-3, 5- dicarboxamide analogues demonstrate notable anti-tubercular activity. In this study, Hantzsch condensation was used to design and synthesize new analogues of dihydropyridine (DHP). Different diary carboxamides were inserted at positions 3 and 5 of the DHP ring. 4(5)-chloro-2-ethyl-5(4)-imidazolyl moiety wa...