The mechanisms of adverse drug reactions in children have been often related to the differences in patient response on pharmacokinetic level. Age-dependent variability in drug metabolizing enzyme systems (DMES) contributes to the wide range of drug responses observed in children. This review provides background information on a variety of DMES in biotransformation phase I and phase II that can ...

Recensión de Nicolás Carrillo Santarelli. FRASER, J. y MCGONIGLE LEYH, B. (Eds.), Intersections of Law and Culture at the International Criminal Court, Edward Elgar Publishing, Northampton MA, 2020, 429 pp.

Using High Throughput Experimentation Approach for the Evaluation of Dehydrogenation Catalysts: Potential Interests and Drawbacks — Linear monoolefins with 10 to 14 carbon atoms are intermediates in the manufacture of biodegradable detergent products. These olefins can be obtained industrially by dehydrogenation of long chain paraffins on specific dehydrogenation catalysts under suitable operat...

Ð Collaborative learning of visual information with computers can be particularly beneficial for acquiring complex and abstract knowledge. This article describes a computer-supported collaborative visual learning environment called TurtleGraph that was designed to assist learners in capturing the concept of recursion as well as recursive programming skills. In this distributed learning environm...

Precursor effects of indium melting have been investigated by means of Mechanical Spectroscopy (MS) and High Temperature X-ray Diffraction (HT-XRD). MS tests evidenced a sharp drop of dynamic modulus in the temperature range between 418 K and 429 K (melting point). At 429 K, HT-XRD showed partial grain re-orientation, peak profile broadening, in particular in the lower part, and peak shift towa...