OBJECTIVE Type 2 diabetes is the most common form of diabetes worldwide. Some of its complications, such as retinopathy and neuropathy, are long-term and protracted, with an unclear etiology. Given this problem, genetic model systems, such as in flies where type 2 diabetes can be modeled and studied, offer distinct advantages. RESEARCH DESIGN AND METHODS We used individual flies in experiment...

Whether or not factors besides hyperphagia influence cellularity of adipose tissue in gold thioglucose (GTG)-treated mice was examined. The animals were treated with GTG (800 mg/kg body weight) or saline as control. Control and one of the GTG-treated groups were given a diet ad libitum and another of the GTG-treated groups was pair-fed to control. In GTG-treated group fed ad libitum, hyperphagi...

General relativity is notoriously difficult to interpret. A "return to the mothers" is proposed to better understand the gothic-R theorem of the Schwarzschild metric of general relativity. It is shown that the new finding is already implicit in Einstein's equivalence principle of 1907 and hence in special relativity (with acceleration). The TeLeMaCh theorem, named onomatopoetically after Telema...

Aim. In this study, we aimed to investigate the effects of febuxostat, a novel inhibitor of xanthine oxidase (XO), on renal damage in streptozotocin- (STZ-) induced diabetic rats. Methods. Diabetes was induced by the intraperitoneal injection of STZ in male Sprague-Dawley rats. Sham-injected rats served as controls. The control and diabetic rats were treated with and without febuxostat for 8 we...

− 162 − Private practice Received: August 30, 2012, Revised: September 21, 2012, Accepted: October 8, 2012 Corresponding author: Shailendra Kapoor, Private practice, Chicago, IL, USA (Tel) 1-865-345-2345 (Fax) 1-865-657-6767 (E-mail) [email protected] C The Korean Society for Thoracic and Cardiovascular Surgery. 2013. All right reserved. CC This is an open access article distributed un...