Business research practice is witnessing a surge in the integration of predictive modeling and prescriptive analysis. We describe framework JANOS that seamlessly integrates two streams analytics, allowing researchers practitioners to embed machine learning models an end-to-end optimization framework. allows for specifying model using standard elements such as constraints variables. The key nove...

Recently there has been an increase in the development and use of Digital Twins manufacturing industry. Different kind models can be developed depending on that is required. There very specific detailed from a particular machine/process oriented to condition monitoring or tool wear degradation, also others full plant planning production. In any case, each these will involve lot parameters (of d...

In 2007, Health Canada proposed a new framework to regulate prescriptive authority for controlled substances, titled New Classes of Practitioners Regulations (NCPR). The new regulatory framework was passed in November 2012; it gives nurse practitioners (NPs), midwives and podiatrists the authority to prescribe controlled medications under the Controlled Drugs and Substances Act. It is expected ...