نتایج جستجو برای: 39
تعداد نتایج: 97137 فیلتر نتایج به سال:
Robertson, J. Gray, David A. Belford, and F. John Ballard. Clearance of IGFs and insulin from wounds: effect of IGF-binding protein interactions. Am. J. Physiol. 276 (Endocrinol. Metab. 39): E663–E671, 1999.—We have examined the role binding proteins have in regulating the clearance of exogenous growth factors from wounds. Hunt-Schilling chambers were subcutaneously implanted in rats, and the c...
The present study was performed to evaluate the in vitro inhibitory potential of sarpogrelate and its active metabolite, M-1, on the activities of nine human cytochrome (CYP) isoforms. Using a cocktail assay, the effects of sarpogrelate on nine CYP isoforms and M-1 were measured by specific marker reactions in human liver microsomes. Sarpogrelate potently and selectively inhibited CYP2D6mediate...
Ikejima, Kenichi, Nobuyuki Enomoto, Vitor Seabra, Ayako Ikejima, David A. Brenner, and Ronald G. Thurman. Pronase destroys the lipopolysaccharide receptor CD14 on Kupffer cells. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G591–G598, 1999.—CD14 is a lipopolysaccharide (LPS) receptor distributed largely in macrophages, monocytes, and neutrophils; however, the role of CD14 in activation...
Nevière, R. R., M. L. Pitt-Hyde, R. D. Piper, W. J. Sibbald, and R. F. Potter. Microvascular perfusion deficits are not a prerequisite for mucosal injury in septic rats. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G933–G940, 1999.—Our major objective was to investigate whether injury to the mucosa of the small intestine occurred in a normotensive model of sepsis and whether such inju...
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