Epigenetic changes may be causal in the ageing process and may be influenced by diet, providing opportunities to improve health in later life. The aim of this review is to provide an overview of several areas of research relevant to this topic and to explore a hypothesis relating to a possible role of epigenetic effects, mediated by sirtuin 1, in the beneficial effects of dietary restriction, i...

The inhibition of the soluble epoxide hydrolase (sEH) is a promising new therapy in the treatment of cardiovascular, inflammation and other disorders. A piperazino functionality as the tertiary pharmacophore remarkably improved the drug-like profile of the 1,3-disubstituted urea sEH inhibitors. However, the potency was more dependent on the overall best balance of the hydrophilicity and lipophi...

Health benefits or advocated health benefits of long-chain (LC) n-3 PUFA are better known by medical doctors as well as by consumers, so that consumption increases. In addition, the development of aquaculture requires more fishmeal and fish oil. Humanisation of care of companion animals is also associated with addition of LC n-3 PUFA in pet foods. The risk of the increased demand for LC n-3 PUF...

this study examined the impact of emotion on customer service and service output deals. the main objective of this study was to investigate the impact of physical environment and social services, the excitement, satisfaction and behavioral intentions of customers and ultimately service outputs. the study of the physical environment has two dimensions and design of physical and social environmen...

abstract background: infants’ feeding is one of the critical periods in women’s health that can influence their life. the purpose of this study was to investigate the relationship between infants’ feeding patterns and mothers’ physical and psychological dimensions of quality of life. materials and methods: in this cross-sectional study, 189 mothers were selected by convenience sampling (n = 63 ...

objective: the aim of this study was to investigate relationship between quality of life and spiritual health and depression in thalasemia major patients in amol city.   method: the research method was correlation. the population was 497 of thalasemia patients. according to the cochrane formula 100 thalasemia patients were selected by random sampling method. the research instruments were qualit...

this study aimed to investigate the relationship between job satisfaction and rganizational citizenship behavior and personality traits city staff lorestan. the research objective of the application and the method of data collection, descriptive, correlative to-be conducted in 1394. the study population of 500 municipal employees lorestan 217 employees were selected using cochran formula the se...

Nicotinamide, one kind of Vitamin B, plays an important role for humans. To ensure quality control of nicotinamide in infant formula, a Certified Reference Material for nicotinamide in infant formula is being prepared in China for the first time. Studying on the procedure of sample preparation and HPLC analysis with different detectors like UV and MS, HPLC-UV and HPLC-IDMS are selected as the v...

OBJECTIVE To summarize evidence about the recurrence of dermatofibrosarcoma protuberans (DFSP) following Mohs micrographic surgery (MMS). DATA SOURCES MEDLINE, Cochrane Library, EMBASE, Pascal, Biosis, CisMef, BDSP, Scopus, and Web of Knowledge databases were searched for the period January 1, 1995, to August 31, 2011. Search terms were Mohs micrographic surgery, dermatofibrosarcoma protuberans...