Keratinocytes produce various pro-inflammatory and profibrotic cytokines that regulate fibroblast function in a paracrine manner. Abnormal changes this effect lead to dysregulated fibrosis diseases such as scleroderma. Protein O-GlcNAcylation is the addition of GlcNAc moiety onto serine or threonine residues proteins. This catalyzed by O-GlcNAc transferase (OGT), removed O-GlcNAcase (OGA). prot...

Factor (F)VIII can be activated to FVIIIa by FXa following cleavages at Arg(372), Arg(740), and Arg(1689). FXa also cleaves FVIII/FVIIIa at Arg(336) and Arg(562) resulting in inactivation of the cofactor. These inactivating cleavages occur on a slower time scale than the activating ones. We assessed the contributions to cleavage rate and cofactor function of residues flanking Arg(336), the prim...

BACKGROUND MicroRNAs, post-transcriptional regulators of eukaryotic gene expression, are implicated in host defense against pathogens. Viruses and bacteria have evolved strategies that suppress microRNA functions, resulting in a sustainable infection. In this work we report that Helicobacter pylori, a human stomach-colonizing bacterium responsible for severe gastric inflammatory diseases and ga...

* Laboratoire de Neurobiologie Humaine, Universite de Provence, Centre de St Jerome, Marseille, France; tlnstitute of Information Transmission Problems, Academy of Sciences, Moscow, Russia; tLaboratoire de Physiologie Neurosensorielle, CNRS, Paris, France Reprint address: J.P. Roll, Laboratoire de Neurobiologie Humaine, URA CNRS 372, Universite de Provence, Centre de SI Jerome, 13397 Marseille ...

* This work was carried out at the Software Automation and Intelligence Laboratory in the Department of Computer Science at Tennessee Technological University as part of our research on intelligent coordinating entities, or ICE. Dr. S. Ramaswamy is an Associate Professor and Chair of the Computer Science Department at Tennessee Technological University. Phone: (931)-372-3691. Email: [email protected]...

INTRODUCTION ..................................................................................... 369 I. LEGAL BACKGROUND ..................................................................... 371 II. ECONOMIC CONTRIBUTIONS ........................................................... 372 III. CURRENT APPROACHES TO FOURTEENTH AMENDMENT ANALYSIS........................................................

..................................................................................................................................................... 367 INTRODUCTION .............................................................................................................................................. 367 PAX GENES, PAIRED DOMAINS AND PAX HOMEODOMAINS .......................................

*Lausanne Institute for Hospitality Research (LIHR), Ecole hôtelière de Lausanne (EHL), Le Chalet-à-Gobet, 1000 Lausanne 25, Switzerland †Competence Center ISnet-VS, University of Applied Sciences Valais, Technopôle 3, 3960 Sierre, Switzerland ‡Hotel Valuation Services HVS, 372 Willis Avenue, Mineola, NY 11501 §University of Western Australia, Faculty of Business, Department of Information Mana...

Citation: Marrari M, Piola AR and Valla D (2017) Variability and 20-Year Trends in Satellite-Derived Surface Chlorophyll Concentrations in Large Marine Ecosystems around South and Western Central America. Front. Mar. Sci. 4:372. doi: 10.3389/fmars.2017.00372 Variability and 20-Year Trends in Satellite-Derived Surface Chlorophyll Concentrations in Large Marine Ecosystems around South and Western...