BACKGROUND Preeclampsia is a hypertensive, multi-system pregnancy disorder whose pathophysiology remains unclear. Elevations in circulating soluble endoglin (sENG) and placental/blood ENG mRNA expression antedate the clinical onset of preeclampsia. This study investigated if endoglin (ENG) pathway genetic variation was also associated with the development of preeclampsia. METHODS We used a ca...

Authors: Steven Devos, Flanders MECHATRONICS Technology Centre, Leuven, Belgium Bert Stallaert, division PMA, Mech. Eng. Dpt., Katholieke Universiteit Leuven Gregory Pinte, Flanders MECHATRONICS Technology Centre Wim Symens, Flanders MECHATRONICS Technology Centre Paul Sas, division PMA, Mech. Eng. Dpt., Katholieke Universiteit Leuven Jan Swevers, division PMA, Mech. Eng. Dpt., Katholieke Unive...

Chihiro Ikuta Dept. of Electrical and Electronics Eng., Tokushima University 2-1 Minami-Josanjima, Tokushima Japan Email: [email protected] Yoko Uwate Dept. of Electrical and Electronics Eng., Tokushima University 2-1 Minami-Josanjima, Tokushima Japan Email: [email protected] Yoshifumi Nishio Dept. of Electrical and Electronics Eng., Tokushima University 2-1 Minami-Josanjima, ...

This article presents information about the development and evaluation of the SF-36 Health Survey, a 36-item generic measure of health status. It summarizes studies of reliability and validity and provides administrative and interpretation guidelines for the SF-36. A brief history of the International Quality of Life Assessment (IQOLA) Project is also included.

This paper reports on the findings of a study to derive a preference-based measure of health from the SF-36 for use in economic evaluation. The SF-36 was revised into a six-dimensional health state classification called the SF-6D. A sample of 249 states defined by the SF-6D have been valued by a representative sample of 611 members of the UK general population, using standard gamble. Models are...

Introduction: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. GIST has been shown to over-express c-KIT (CD117), the receptor tyrosine kinase. Imatinib (STI571 or Glivec) is a new type of tyrosine kinase inhibitor that selectively inhibits various tyrosine kinases and has been successfully used to treat GIST. In this study we have...