The aim of this work was to determine if the inhibition or stimulation of NO synthesis modulates liver damage induced by chronic lead intoxication. Lead nitrate (3.6 mg/kg, per os) was administered one time a day for 30 days to male Wistar rats with low and high resistance to hypoxia treated simultaneously with L-arginine (600 mg/kg, i.p.) or N-nitro-L-arginine (L-NNA, 35 mg/kg, i.p.) 30 min. b...

A class of r.e. degrees, called the array nonrecursive degrees, previously studied by the authors in connection with multiple permitting arguments relative to r.e. sets, is extended to the degrees in general. This class contains all degrees which satisfy a 00 > (a 0 0) 0 (i.e. a 2 GL 2) but in addition there exist low r.e. degrees which are array nonrecursive (a.n.r.). Many results for GL 2 deg...

BACKGROUND A few recent studies have demonstrated heightened hypothalamic-pituitary-adrenal (HPA) axis reactivity to acute stress in animals exposed to heavy metal contaminants, particularly lead. However, Pb-induced dysregulation of the HPA axis has not yet been studied in humans. OBJECTIVE In this study, we examined children's cortisol response to acute stress (the glucocorticoid product of...

The concentration of airborne and blood lead (Pb) was assessed in a Pb acid battery recycling plant and in a Pb acid battery manufacturing plant in Kenya. In the recycling plant, full-shift area samples taken across 5 days in several production sections showed a mean value ± standard deviation (SD) of 427 ± 124 μg/m(3), while area samples in the office area had a mean ± SD of 59.2 ± 22.7 μg/m(3...

Lead poisoning in this country for the most part is a disease of industry and hence is usually met with in the adult. But the condition may be met with at any age and in some countries, e.g., Australia and Japan, it seems to be not uncommon in childhood. However, everywhere except perhaps in Japan it is rare during infancy, and, as the symptomatology during this period of life is often obscure ...