It is desirable and necessary to reexamine the influences of stock andl scion oIn alkaloid synthesis and transformation using plants which behave differently witlh respect to alkaloid formation (4). Experiments were conducted in the greenhouse for 3 years in an attempt to separate the effects of root, or stock, from those of the top, or scioIn, on alkaloid synthesis and transformation. Some of ...

Glycoglycerolipids occur widely in natural products, especially in the marine species. Glycoglycerolipids have been shown to possess a variety of bioactivities. This paper will review the different methodologies and strategies for the synthesis of biological glycoglycerolipids and their analogs for bioactivity assay. In addition, the bioactivities and structure-activity relationship of the glyc...

Inflammation is a response to acute tissue damage due to physical injury, infection, exposure to toxins and ischemic injury. The persistent inflammatory responses in or around developing neoplasm regulate many aspects of tumor progression. Natural plant based alkaloids are often have greater pharmacological effects and are used as medications as local anesthetic, stimulant, analgesic, anti-bact...

Gregor Breckle, Kurt Polborn, and Thomas Lindel Ludwig-Maximilians-Universität München, Department of Chemistry, Butenandtstr. 5Ð13, D-81377 Munich, Germany Reprint requests to Prof. Dr. Th. Lindel. Fax int: +(0)89/2180-7-7734. E-mail: [email protected] Z. Naturforsch. 58b, 451Ð456 2003; received February 17, 2003 The marine pyrrole-imidazole alkaloid sventrin (1) and the hither...

Biodiversity in the seas is only partly explored, although marine organisms are excellent sources for many industrial products. Through close co-operation between industrial and academic partners, it is possible to successfully collect, isolate and classify marine organisms, such as bacteria, fungi, micro- and macroalgae, cyanobacteria, and marine invertebrates from the oceans and seas globally...

The predominant alkaloids in lotus leaves are aporphine alkaloids. These are the most important active components and have many pharmacological properties, but little is known about their biosynthesis. We used digital gene expression (DGE) technology to identify differentially-expressed genes (DEGs) between two lotus cultivars with different alkaloid contents at four leaf development stages. We...

Nucleosides are glycosylamines that structurally form part of nucleotide molecules, the building block of DNA and RNA. Both nucleosides and nucleotides are vital components of all living cells and involved in several key biological processes. Some of these nucleosides have been obtained from a variety of marine resources. Because of the biological importance of these compounds, this review cove...

There are numerous biologically active substances with novel structures and unique physiological functions in marine organisms. These substances are important sources of new lead compounds. Pelorol is a natural product isolated from marine organisms that possesses a novel structure with high bioactivity. In this paper, the synthesis of pelorol has been completed, and the synthesis of some inter...