conclusions due to the significant reduction in the mean inactivation dose of colon cancer cells in the presence of gold nanoparticles, it seems that gnps are suitable options to achieve a new approach in order to improve radiotherapy efficiency without increasing the prescribed radiation dose. results cell survival in the presence of gnps was more than 90% and the maximum uptake of gnps was ob...

IntroductionTo compare neurocognitive functioning in patients with SCLC who received prophylactic cranial irradiation (PCI) or without hippocampus avoidance (HA).MethodsIn a multicenter, randomized phase 3 trial (NCT01780675), were to standard PCI HA-PCI of 25 Gy 10 fractions. Neuropsychological tests performed at baseline and 4, 8, 12, 18, 24 months after PCI. The primary end point was total r...

Guidelines on immunoprophylaxis for prevention of RSV infection recommend it in preterm babies born before 29 wGA; in babies affected by bronchopulmonary dysplasia or congenital heart defects; and in post-heart transplantation patients. On the contrary, immunoprophylaxis is not recommended in preterm babies born between 29 and 35 wGA. We evaluated the impact of RSV-related healthcare expenditur...

Adalimumab is a well-tolerated and effective biologic treatment for psoriasis. Given its efficacy biosimilar availability, it often first-line biologic. Clinical trial data have demonstrated that dose escalation from fortnightly to weekly an safe strategy. However, real-world lacking; therefore we aimed assess patient response in the clinical setting. We reviewed records of patients treated wit...

BACKGROUND Nutritional rickets is a growing global public health concern despite existing prevention programmes and health policies. We aimed to compare infant and childhood vitamin D supplementation policies, implementation strategies and practices across Europe and explore factors influencing adherence. METHODS European Society for Paediatric Endocrinology Bone and Growth Plate Working Grou...

Spontaneous quadruplet is rarely seen. Quadruplet pregnancy is accompanied with severe complications such as abortion , premature labor , first trimester vaginal bleeding , anemia and …etc . Our patient was a 29- year old lady with history of first pregnancy twin that was aborted. In the second pregnancy at three months of gestation sonography showed quadruplet pregnancy so cerclage was perfo...

In many countries, policymakers have used urban densification strategies in an effort to create more sustainable cities. However, spatial density as a concept remains unclear and complex. Little information exists about how density is considered by decision makers, including the different kinds of density and the wider political and economic context in which decisions are made: who makes densit...

Effects of anti-tobacco and anti-marijuana TV advertisements on explicit (i.e., semantic differential ratings) and implicit (i.e. Implicit Association Test, IAT) attitudes toward tobacco and marijuana were compared. Two hundred twenty nine, 18- to 19-year-old U.S. college students were randomly assigned to anti-tobacco or anti-marijuana PSA viewing conditions. Participants completed a short sur...

The aim of this study was to investigate the prerace and during-race carbohydrate intakes of elite-level triathletes contesting draft-legal Olympic-distance triathlon (ODT) events. Self-reported prerace and during-race nutrition data were collected at 3 separate ODT events from 51 elite senior and under-23 triathletes. One hundred twenty-nine observations of food and fluid intake representing a...