A number of gangliosides were isolated from cat and sheep erythrocytes for use in analyzing the specificity of a panel of human anti-heterophile monoclonal antibodies. The structures of these compounds were determined by a combination of different procedures, including sugar analysis, glycosidase treatment, periodate oxidation, TLC immunostaining, methylation analysis, and mass spectrometry. Th...

The fragmentation of underivatized and peracetylated maltooligosaccharides, ranging in length from four to seven glucose residues, has been investigated by 252Cf plasma desorption mass spectrometry (PDMS). Investigations are made of the effects on the mass spectra of (1) peracetylation, (2) sample preparation by electrospray deposition onto metallic substrates versus adsorption onto nitrocellul...

The NCRP Wound Model, which describes the retention of selected radionuclides at the site of a contaminated wound and their uptake into the transfer compartment, has been combined with the ICRP element-specific systemic models for those radionuclides to derive dose coefficients for intakes via contaminated wounds. These coefficients can be used to generate derived regulatory guidance (i.e., the...