BACKGROUND Studies of workers at the plutonium production factory in Hanford, WA have led to conflicting conclusions about the role of age at exposure as a modifier of associations between ionising radiation and cancer. AIMS To evaluate the influence of age at exposure on radiation risk estimates in an updated follow up of Hanford workers. METHODS A cohort of 26 389 workers hired between 19...

introduction: the low regeneration of bone in defective bones causes therapeutic problems. various strategies to assess the healing of bone defects have been used which they include histological and histo-chemical analysis in an invasive study. the purpose of this study was to determine the ultrasonic parameters of bone as a promising noninvasive technology for assessing bone repair process. ma...

INTRODUCTION Thymic carcinoma is a rare and aggressive thymic neoplasm. The European Society of Thoracic Surgeons developed a retrospective database collecting patients undergoing resection for thymic tumors from 1990 to 2010. METHODS Of 2265 patients with thymic tumors, there were 229 thymic carcinomas. Clinicopathological characteristics were analyzed including age, associated paraneoplasti...

Initial results are presented concerning the verification of operational SCIAMACHY near–infrared (NIR) Level 1 nadir radiance spectra and corresponding Level 2 near–realtime (NRT) BIAS data products such as CH4, CO, and H2O total column amounts. The focus of this study is channel 8 (2265–2380 nm). The verification approach used here is based on applying an independent retrieval method (WFM–DOAS...

BACKGROUND Despite considerable knowledge about musculoskeletal disorders (MSD) and physical, psychosocial and individual risk factors there is limited knowledge about physical activity as a factor in preventing MSD. In addition, studies of physical activity are often limited to either leisure activity or physical activity at work. Studies among military personnel on the association between phy...

Membranes enriched in photosystem II were isolated from spinach and further solubilised using n-octyl beta-D-glucopyranoside (OctGlc) and n-dodecyl beta-D-maltoside (DodGlc2). The OctGlc preparation had high rates of oxygen evolution and when subjected to size-exclusion HPLC and sucrose density gradient centrifugation, in the presence of DodGlc2, separated into dimeric (430 kDa), monomeric (236...

OBJECTIVE To quantify differences in resource expenditure in the perinatal period and long-term outcome of extremely premature infants who received systematically different approaches to neonatal intensive care. METHODS Perinatal management, mortality, prevalence of disabling cerebral palsy (DCP), and resource expenditure of 2 population-based inception cohorts of extremely premature infants ...

with amino acids in cell culture (SILAC), which provides an elegant method for the incorporation of an isotopic label into proteins prior to MS-based proteomics.18 In a SILAC experiment, two cell populations are grown in culture media that are identical except that one of them contains a “light”(natural abundance) and the other a “heavy”(isotopically enriched) form of a particular amino acid (u...

OBJECTIVE The Healthy Steps for Young Children Program (HS) incorporates early child development specialists and enhanced developmental services into routine pediatric care. An evaluation of HS is being conducted at 6 randomization and 9 quasi-experimental sites. Services received, satisfaction with services, and parent practices were assessed when infants were aged 2 to 4 months. METHODS Tel...

We recently demonstrated that the cytotoxicity of nineteen 1,2,3,4-tetrahydroisoquinoline derivatives depends on the molecular size (surface area, volume, width measured at 3-dimensional configuration), but not on most of the other electronic factors (Ishihara et al., Anticancer Res 29: 2265-2272, 2009). However, the information regarding cytotoxicity and molecular size in these compounds is li...