Sensitive enzyme-linked immunosorbent assays (ELISA) for the detection of human T cell antigens in soluble form have been developed. The assays use mouse monoclonal antibodies and specific anti-Leu sera prepared in rabbits by immunizing with Leu antigens absorbed to monoclonal antibody affinity columns. With these assays, Leu-1, -2, and -3 antigen signals from extracts of as few as 5 X 10(3) ce...

This work describes the molecular properties of a human pancreatic adenocarcinoma-associated mucin-like antigen defined by a murine monoclonal antibody (DU-PAN-2). DU-PAN-2 antigen is a large molecule, readily detected in the body fluids of patients with pancreatic adenocarcinoma and sensitive to neuraminidase treatment and alkaline reduction. The antigen binding activity of the DU-PAN-2 immuno...

Objectives: Mono or infectious mononucleosis (IM) is often referred to as the kissing illness. Epstein-Barr virus (EBV), which causes mono, spread by saliva. Kissing, sharing a drink, eating utensils with person who has can transmit disease healthy individuals. This study investigates several bioactive compounds derived from plants forecast how effective plant-based ligands will be at preventin...

Antigen-induced eosinophil recruitment into the airways of sensitized mice is mediated by CD41 T cells and their cytokines, especially IL-5. In this study, we found that the antigen-induced airway eosinophilia was diminished in Stat5adeficient (Stat5a2/2) mice and Stat5bdeficient (Stat5b2/2) mice. We also found that antigen-induced CD41 T-cell infiltration and IL-5 production in the airways wer...

This work describes the molecular properties of a human pancreatic adenocarcinoma-associated mucin-like antigen de fined by a murine monoclonal antibody (DU-PAN-2). DU-PAN-2 antigen is a large molecule, readily detected in the body fluids of patients with pancreatic adenocarcinoma and sensitive to neuraminidase treatment and alkaline reduction. The antigen binding activity of the DU-PAN-2 ¡mmu...

Breast cancer remains one of the most frequent malignancies in women and primary cause cancer-related death all over world. Hormones tumor biomarkers have been implicated as possible causes prognostic breast cancer. The present study investigated use serum hormonal levels biomarkers; Carcinoembrvonic antigen (CEA), (CA 15-3) for diagnosis Cancer, generation different subtypes using Estrogen rec...