Five isoforms of APAF1 cDNA have been identified in Homo sapiens: The original APAF1 (also called Apaf-1S) is 3585 bp long (it contains 12 WD40 repeats); The APAF1-1M isoform (3618 bp) contains an insertion of 33 nt after position 295 of the first published sequence (11 aa insertion GKDSVSGITSY between aa 98 and 99; it also contains 12 WD40 repeats); The APAF1XS isoform (3516 bp) contains the s...

The TEMPOL-TEMPOL radial distribution functions (RDFs) calculated from the 1M TEMPOL simulations are shown in Fig. S1. While the TEMPOL molecules are seen to be well dispersed in acetone and DMSO*, a very small tendency of the radicals to stay closer to each other is seen in the simulation with DMSO. The near-near (NN) and near-far (NF) contributions to the TEMPOL-solvent dipolar time correlati...

The prevalence of non-communicable diseases (NCDs) and NCD risk factors in Malaysia have risen substantially in the last two decades. The Malaysian Ministry of Health responded by implementing, "The National Strategic Plan for Non-Communicable Diseases (NSP-NCD) 2010-2014", and the "NCD Prevention 1Malaysia" (NCDP-1M) programme. This paper outlines the primary health system context in which the...

A dynamic feedback system is developed for estimating the headway and velocity in a longitudinal three-vehicle platoon. The estimation system is modeled using a particle filter (PF) and an unscented Kalman filter (UKF) that estimate them by measuring the acceleration rate and/or velocity of probe vehicle(s) in the platoon. State equations are defined as a discrete conservation equation of headw...

Classical molecular dynamics simulations with polarizable potential models were carried out to quantitatively determine the effects of KCl salt concentrations on the electrostatic surface potentials of the vapor-liquid interface of water. To the best of our knowledge, the present work is the first calculation of the aqueous electrolyte surface potentials. Results showed that increased salt conc...

This paper shows the viability of precise indoor localization using physical layer information in WiFi systems. We find that channel frequency responses across multiple OFDM subcarriers can be suitably aggregated into a location signature. While these signatures vary over time and environmental mobility, we notice that their core structure preserves certain properties that are amenable to local...

This paper presents an efficient architecture for performing 128 points to 1M points Fast Fourier Transformation (FFT) based on mixed radix-2/4/8 butterfly unit. The proposed FFT architecture reduces the computation cost by taking the advantage of the radix-8 FFT algorithm while remaining compatible with sequences whose data length is an integral power of 2. Further optimizations for reconfigur...

A 1,000 nm wide supercontinuum, spanning from 1470 nm in the telecom band to 2470 nm in the mid-infrared is demonstrated in a 800 nm x 220 nm 1 cm long hydrogenated amorphous silicon strip waveguide. The pump source was a picosecond Thulium doped fiber laser centered at 1950 nm. The real part of the nonlinear parameter of this waveguide at 1950 nm is measured to be 100 ± 10 W -1m-1, while the i...

Streptococcus sanguinis forms part of the oral biofilm, has a decisive role in development prevalent diseases and acts as an opportunistic pathogen at systemic level.  Aims: To evaluate vitro effects xylitol on bacterial growth against (ATCC 10556).  Methods: The study sample was distributed into 6 groups: 4 experimental groups (1M; 0,75M; 0,50M 0,25M xylitol), negative control (disti...