Dysregulation of microRNAs (miRs) can contribute to cancer development and progression. In the present study, the function and underlying molecular mechanisms of miR-320 in breast cancer tumorigenesis and progression were investigated. The results of a reverse transcription-quantitative polymerase chain reaction analysis demonstrated that miR-320 was frequently downregulated in breast cancer ti...

Ethanol extract (ETE) and cold aqueous infusion (CAI) of Vitex leucoxylon leaf were evaluated in a battery of tests to define the activity profile of the plant. CAI depressed SMA, antagonised d-amphetamine stereotypy and oxotremorine tremors, shortened the duration of mice immobility in behavioural 'despair' test and lowered serum total cholesterol level. ETE showed significant inhibition of ca...

Phillipa Caudwell, Catherine Gibbons, Mark Hopkins, Erik Naslund, Neil King, Graham Finlayson and John Blundell* Institute of Psychological Sciences, Faculty of Medicine and Health, University of Leeds, Leeds LS2 9JT, UK Sport, Health, Leisure and Nutrition, Leeds Trinity University College, Brownberrie Lane, Horsforth, Leeds LS18 5HD, UK Clinical Sciences (Division of Surgery), Danderyd Hospit...

The pharmacokinetic studies of enrofloxacin were investigated in yak (Bos grunniens L.) after administration of enrofloxacin by intramuscular route at 5 mgkg-1 body weight. Blood samples were collected from the jugular vein at predetermined time intervals after drug administration. Plasma was separated and analysed for enrofloxacin by reverse-phase high performance liquid chromatography. Variou...

Glioma is the most common cancer in human brain system and seriously threatens human health. miRNA-320 has been demonstrated to be closely correlated with the development of glioma. However, its effect and molecular mechanism underlying radioresistance have not been fully elucidated in glioma. Here, RT-qPCR assay was used to assess the expressions of miR-320 and forkhead box protein M1 (FoxM1) ...

Selon les données récentes des comptes nationaux, le rythme de croissance l’économie belge s’est sensiblement raffermi en début d’année, PIB national ayant augmenté 0,5% entre décembre 2022 et mars 2023. Il ressort par ailleurs l’évolution récente plusieurs indicateurs conjoncturels que a progressé au même soutenu cours du 2ème trimestre.
 Malgré repli important prix l’énergie, la ne devra...

Various solution-treatments were applied on a rapidly solidified and subsequently rolled Mg-7.50Al-1.07Ca-0.17Mn (mass%) alloy sheet, room-temperature stretch formability, tensile properties, microstructures, textures of the solution-treated sheets have been investigated. Although solution-treatment at 400 °C gives high strengths, sheet shows poor formability with Index Erichsen value 4.8 mm du...

Abstract In this study, 45Si2MnCr2Mo steel was fabricated by casting, hot rolling, and normalizing, followed tempering at different temperatures from 180 to 520 °C for 2 h. Special attention paid the effects of on microstructure mechanical properties steel. The results indicate that tempered consists bainite, martensite, retained austenite (RA), it is not sensitive below 320 °C. However, after ...