The main feature of this new approach to platelet freezing is a controlled rate of addition and postthaw removal of 5#{176}/odimethylsulfoxide (DMSO). When DMSO was removed from fresh nonfrozen platelet concentrates before transfusion, no adverse effect on posttransfusion survival was observed. The 51Cr recovery of autologous fresh platelet concentrates in vivo was 65#{176}/o ± 5#{176}/o, while...

Immunologic abnormalities in patients with cirrhosis strongly correlate with severity of liver cirrhosis. The association between cirrhosis and human herpesvirus type 8 (HHV-8) infection is unclear. Plasma samples were obtained from 74 healthy control subjects and 59 patients with cirrhosis. The seropositive rates for HHV-8 antibodies in patients with cirrhosis (25/59 [42%]) were significantly ...

C(R ;R) is the space of m-times, continuously differentiable funtions, C b (R ;R) is the subspace of C(R ;R) whose elements have bounded derivatives of all orders less than of equal to m, C c (R ;R) is the subspace of C b (R ;R) whose elements have compact support, C 1,2 b ( [0,∞)×R ;R) is the space functions (t,x) ∈ [0,∞) × R 7−→ u(t,x) ∈ R which have one bounded, continuous derivative with re...

Mycobacterium leprae (M. leprae) as alternative to current WHO MDT. Individual drugs tested were Rifampicin (RMP), Rifapentine (RPT) and Moxifloxacin (MOXI). Drug combinations were RMP, Clarithromycin (CLARI), Minocycline (MINO) and RMP, MINO and Ofloxacin (OFLO). RPT drug combinations were RPT, CLARI, MINO and RPT, OFLO, MINO. Both the drugs and drug combinations were used as daily regimen and...

Clostridium difficile infection (CDI) is the main cause of hospital-acquired diarrhea that can cause colitis or even death. The medical-treatment cost and deaths caused by CDI are increasing annually worldwide. New approaches for prevention and treatment of these infections are needed, such as the use of probiotics. Probiotics, including Bifidobacterium spp. and Lactobacillus, are microorganism...

We describe the radiographic measurement of the angle of tilt of the patella and relate it to malalignment of the extensor mechanism. The tilt angle is defined as the angle subtended by a line joining the medial and lateral edges of the patella and the horizontal. The radiograph (Merchant type) is taken with the foot pointing up, the lower edge of the film parallel to the ground, and the knee a...

Abstract Introduction Effective communication skills are an extremely important aspect of good medical practice. Fractures common with over 1 million fractures occurring each year in the UK; which 5-10% may have problems healing. Patient perceptions factors harmful to fracture healing process unknown and our study investigates this. Method A total 418 responses were collected from participants ...