The weak inward rectifier potassium channel ROMK is important for water and salt reabsorption in the kidney. Here we identified Golgin-160 as a novel interacting partner of the ROMK channel. By using yeast two-hybrid assays and co-immunoprecipitations from transfected cells, we demonstrate that Golgin-160 associates with the ROMK C-terminus. Immunofluorescence microscopy confirmed that both pro...

À la fin des années 1980, Paul Virilio (1988) observe la délégation croissante de l’œil humain par les machines vision. Le régime images automatisées est caractérisé l’« aveuglement » machines. Cet article propose réfléchir aux rapports entre œil et vision computationnelle manières do...

1MD, Faculdade Evangélica do Paraná, Curitiba PR, Brazil; 2MD, Medical Genetic Service, Hospital de Clínicas de Porto Alegre RS, Brazil; 3MD, PhD, Neurophysiologist, Neurology Division, Internal Medicine Department, Hospital de Clínicas, Universidade Federal do Paraná, Curitiba PR, Brazil; 4MD, PhD, Medical Genetic Service, Hospital de Clínicas de Porto Alegre RS, Brazil; 5MD, PhD, Group for Ad...

The oligodendrocyte-derived extracellular matrix glycoprotein J1-160/180 is a recognition molecule expressed exclusively in the central nervous system. J1-160/180 has been shown to be adhesive for astrocytes and repellent towards neurons and growth cones. We report here the complete nucleotide sequence of J1-160/180 in the rat. The predicted amino acid sequence showed a structural architecture ...

Golgin-160 is ubiquitously expressed in vertebrates. It localizes to the cytoplasmic side of the Golgi and has a large C-terminal coiled-coil domain. The noncoiled-coil N-terminal head domain contains Golgi targeting information, a cryptic nuclear localization signal, and three caspase cleavage sites. Caspase cleavage of the golgin-160 head domain generates different fragments that can transloc...

En 1939, une longue étude consacrée au Code de la famille paraît dans section doctrinale Gazette du Palais, sous plume professeur droit civil, Paul Esmein. Dans les « Généralités », l’auteur s’arrête sur principes inspirateurs des dispositions prises par le gouvernement Daladier en matière famille, démographie et natal...

Thrombospondin, the major glycoprotein released from alpha-granules of thrombin-stimulated platelets, is a disulfide-bonded trimer of 160 kilodalton subunits and apparently functions as a platelet lectin. Because cultured human umbilical vein endothelial cells synthesize and secrete a glycoprotein (GP-160) which is a disulfide-bonded multimer of 160 kdalton subunits, the possibility that GP-160...

The partial sequence of a gene encoding the COOH terminus of a protein of apparent molecular weight of 160 kD associated with the flagellum of trypomastigotes of Trypanosoma cruzi (FL-160 now renamed to FL-160-1) has been previously reported. The COOH terminus of FL-160-1 has an epitope, defined by 12 amino acids, which molecularly miMics a nervous tissue antigen of 48 kD found in myenteric ple...

Typologies, taxinomies, classifications : de nombreuses confusions règnent autour ces notions mobilisées dans les travaux procédant à des comparaisons en politique comparée et s’appuyant sur l’élaboration « types ». Cet article vise clarifier usages identifiant quatre formes typologie, distinguer selon le mode d’élabo...