Steady state mRNA levels in various human tissues reveal that the proinflammatory cytokine IL-18 is constitutively and ubiquitously expressed. However, limited IL-18R alpha-chain (IL-18Ralpha) expression in tissues may restrict ligand-acting sites and contribute to a specific response for IL-18. To study the IL-18R complex, [(125)I]IL-18 was studied for binding to the cell surface receptors of ...

Little is known about the repertoire of MAGE-A3 CD4(+) T-cell epitopes recognized in vivo by neoplastic patients and how antigen processing influences epitope formation. Here, we first show that MAGE-A3-specific CD4(+) T cells are present in the blood of advanced melanoma patients. MAGE-A3(111-125), MAGE-A3(191-205), and MAGE-A3(281-300) were recognized by 7, 6, and 5 of the 11 patients tested,...

en 1994, 125 carcases of camel (100 from isfahan and 25 from yazd) in slaughter - houses were studied for parasitic infections. seventy percent of the camels were infected with hydatid cyst and half of the males (50%) had testicular filaria identified as dipetalonema evansi. all the infected male camels except 3, demonstrated sheathed rnicrofilariae in their peripheral blood smears. although so...

The world economy has experienced a considerable shift in structure from the late 1980s, with service sector contributing approximately 62 percent to overall economic output and 50 of total employment share 1991 2010. Given importance sector, we study inter￾relationship between female education attainment, per capita value-added growth sector. Our analysis uses data 146 countries – 2015. Using ...

OBJECTIVE To determine the validity of glycosylated hemoglobin (HbA1c) values as a method to diagnose type 2 diabetes mellitus (DM2) in a population at risk seen in primary care. DESIGN Cross-sectional analytical study. SETTING Data were obtained for the Raval Sud study population (epidemiologic study of alterations in glucose metabolism in a population at risk). PARTICIPANTS 454 subjects...