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form (18). Address for reprint requests: J. M. Pascual, Department of Neurology, Box 164, Neurological Institute of New York, 710 W. 168th St.,

Dysfunctional mitochondria are central in the pathogenesis of diabetic cardiomyopathy. Mitochondrial proteomic alterations resulting from diabetes mellitus have been reported although the mechanisms driving changes in proteomic signatures are unknown. microRNAs (miRNAs) have been considered as potential regulators of proteins. The goal of this study was to determine whether miRNAs play a role i...

Aberrant expression of miR-141 has recently implicated in the occurrence and development of various types of malignant tumors. However whether the involvement of miR-141 in the pathogenesis of glioma remains unknown. Here, we showed that miR-141 was markedly downregulated in glioma tissues and cell lines compared with normal brain tissues, and its expression correlated with the pathological gra...

1 Institute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan 2Department of Medical Research, Chung Shan Medical University Hospital, Taichung 402, Taiwan 3Graduate Institute of Applied Living Science, Tainan University of Technology, Tainan City 710, Taiwan 4Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119077 5 Tissue ...

1. Macias-Hernandez SI, Vasquez-Sotelo DS, Ferruzca-Navarro MV, Badillo Sanchez SH, Gutierrez-Martinez J, Nunez-Gaona MA, et al. Proposal and evaluation of a telerehabilitation platform designed for patients with partial rotator cuff tears: a preliminary study. Ann Rehabil Med 2016;40:710-7. 2. Kang JH, Bae HJ, Choi YA, Lee SH, Shin HI. Length of hospital stay after stroke: a Korean nationwide ...

1 Zhejiang Provincial Key Laboratory of Applied Enzymology, Yangtze Delta Region Institute of Tsinghua University, Jiaxing 314006, P. R. China. 2 College of Biological and Environmental Sciences, Zhejiang Wanli University, Ningbo 315100, P. R. China. 3 Molecular Inflammation Research Center for Aging Intervention (MRCA), College of Pharmacy, Pusan National University, Busan 609-735, Korea. 4 De...

Apolipoprotein (apo) E, via its receptor binding domain contained in residues 140-150, mediates hepatic and peripheral tissue binding of cholesterol-rich lipoproteins. Previously, we reported that a synthetic peptide representing a linear tandem repeat of amino acids 141-155, the 141-155 dimer, binds the low density lipoprotein (LDL) receptor. To define the structural features essential for LDL...