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Metrics such as relative hazards and relative risks do not account for the prevalence of a marker over time and its relation to whether and when an outcome occurs. Uncommon markers that have good predictive values and common markers that are poorly predictive may not be (clinically) useful in predicting disease and other health outcomes. Recent work by Little et al. (Am J Epidemiol. 2011;173(12...
Energy expenditure and fat-free mass (FFM), as well as the relationships between these parameters, were investigated in thirteen pairs of monozygotic twins discordant for SCI. Basal energy expenditure (BEE) and resting energy expenditure (REE) were determined by indirect calorimetry. Measurements for FFM and fat mass were obtained by dual-energy x-ray absorptiometry. Total body potassium was de...
In a prospective epidemiologic study in company employees in Westfalia aimed at improving early diagnosis of coronary heart disease in 3069 men and 1387 women, concentrations of HDL-apolipoprotein A-I and HDL-cholesterol were measured and the results were correlated with several risk factors of coronary heart disease. A negative correlation between hypertriglyceridaemia and HDL-cholesterol (r =...
D ESPITE its attended complications. immunosuppression for graft acceptance and the impending threat of chronic rejection are two of the many overwhelming factors that have necessitated the implementation of strategies aimed at inducing donor-specific tolerance (OST). With the postulation that persistence of donor cell chimerism after organ transplantation (Tx) may play a notable role in allogr...
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