Anthrax vaccine adsorbed (AVA), an effective countermeasure against anthrax, is administered as six subcutaneous (SQ) doses over 18 months. To optimize the vaccination schedule and route of administration, we performed a prospective pilot study comparing the use of fewer AVA doses administered intramuscularly (IM) or SQ with the current schedule and route. We enrolled 173 volunteers, randomized...

This paper addresses a multi-stage stochastic integer programming formulation of the uncapacitated lot-sizing problem under uncertainty. We show that the classical (`, S) inequalities for the deterministic lot-sizing polytope are also valid for the stochastic lot-sizing polytope. We then extend the (`, S) inequalities to a general class of valid inequalities, called the (Q, SQ) inequalities, an...

OANA M. DUICU1,2, ILEANA SCURTU1, ROXANA POPESCU3, ADRIAN STURZA1,2, DORINA CORICOVAC4, MARIA D. DANILA1,2, ANDREEA PRIVISTIRESCU1, DANINA M. MUNTEAN1,2,* 1“Victor Babes” University of Medicine and Pharmacy Timisoara, Department of Pathophysiology, 2 Eftimie Murgu Sq., 300041, Timisoara, Romania 2“Victor Babes” University of Medicine and Pharmacy Timisoara, Center for Translational Research and...

CARMEN SOFICA TATU1,2#, CARMEN PANAITESCU1,2#, LAURA MARUSCIAC1#, ALINA MARIA SISU3#, MIRABELA CRISTEA2, DANIELA ANCA PUSCASIU4*, GABRIELA TANASIE1,2 1Victor Babes University of Medicine and Pharmacy Timisoara, Functional Sciences Department, Physiology Discipline, 2 Eftimie Murgu Sq., 300041, Timisoara, Romania 2OncoGen Centre, 2 Eftimie Murgu Sq., 300041, Timisoara, Romania 3Victor Babes Univ...

For a graph G, let V ar(G) denote the variance of the degree sequence of G, let sq(G) denote the sum of the squares of the degrees of G, and let t(G) denote the number of triangles in G and in its complement. The parameters are related by: V ar(G) = sq(G)/n− d where d is the average degree of G, and t(G) = ( n 3 ) + sq(G)/2−m(n− 1). Let V ar(n) denote the maximum possible value of V ar(G) where...

Amplification of the MYCN gene in neuroblastomas is a potent biological marker of highly aggressive tumors, which are invariably fatal unless sound clinical management is applied. To determine the usefulness of semi-quantitative differential PCR (SQ-PCR) for accurate quantification of MYCN gene copy number, we evaluated the analytical performance of this method by comparing the results obtained...

Condominium management (CM) businesses rely on continuous improvements to service quality (SQ) to increase consumer satisfaction (CS) and thereby improve operations. Lacking knowledge of SQ and CS results in poor efficiency. To develop cost-effective strategies for improvements, the relationship between SQ and CSmust be investigated. This work proposes novel procedures to explore the relationsh...

Regular magnetic daily quiet time (Sq) variations in total intensity of about 30 nT amplitude are determined in Universal Time (UT) from satellite magnetic field measurements. The CHAMP satellite traverses all hours of local time in 132 days and the Sq variations in total intensity are therefore calculated as an average over the 132 days for each hour of UT. Results are compared with the Sq dai...

Active dendrites can be viewed as linear classi"ers augmented by a few second-order product terms representing multiplicative synaptic interactions [4]. To quantify the degree to which local synaptic interactions could augment the memory capacity of a neuron, we have studied the family of `subsampled quadratica (SQ) classi"ers. Each SQ classi"er is a linear classi"er augmented by a subset k of ...