miR-128, a brain-enriched microRNA, has been implicated in the control of neurogenesis and synaptogenesis but its potential roles in intervening processes have not been addressed. We show that post-transcriptional mechanisms restrict miR-128 accumulation to post-mitotic neurons during mouse corticogenesis and in adult stem cell niches. Whereas premature miR-128 expression in progenitors for upp...

Sleep plays a vital role in regulating physiological mechanisms in the human body. Nowadays, by the change of lifestyle and as a consequence of longer work hours and increased accessibility to media, sleep disturbance becomes a common problem in modern society. Many studies demonstrated that sleep disturbance triggers a systemic low-grade inflammation by increasing the level of several cytokine...

The colorectal cancer is the leading contributor of cancer-related mortality. Mammalian target of rapamycin (mTOR), existing in 2 complexes (mTORC1/2), is frequently dysregulated and constitutively activated in colorectal cancers. It represents an important drug target. Here we found that INK-128, the novel ATP-competitive kinase inhibitor of mTOR, blocked both mTORC1 and mTORC2 activation in c...

MicroRNAs (miRNAs) are small, non-coding RNAs which regulate gene expression at the post-transcriptional level. Abnormal expression of miRNAs occurs frequently in human tumors. Despite the fact that reduced expression of miR-128 has been observed in glioma tissues and cells, the role of miR-128 in tumors has not been fully characterized. In the present study, cell adhesion assays indicated that...

Mundja is a MAC generation algorithm that has been designed for use together with a stream cipher. Mundja accumulates the message onto two independent registers: the first is a Cyclic Redundancy Checksum (CRC) that uses linear feedback; the second is a strengthened version of the SHA-256 register [5] that uses nonlinear feedback. Mundja is fast (asymptotically about 4 times the speed of HMAC-SH...

128-EIA3 is an integrity algorithm considered for adoption as a third integrity algorithm by European Telecommunication Standard Institute (ETSI) for 4th generation of GSM networks.128-EIA3 is vulnerable to birthday forgery attack. Birthday forgery attack requires minimum 2 known message-MAC pairs for finding collision in 128-EIA3. 128-EIA3 is susceptible to internal collision of its universal ...

An important objective of the MicroUnity mediaprocessor is to allow the design of systems that replace hardwired functionality with software. One of the key design techniques that has been employed at the architectural level is an instruction set that processes 128-bit vectors of data of varying widths. This introduces the challenge of writing software that effectively uses the available vector...

In this paper, we present an enhanced cryptanalysis of the Substitution Cipher Chaining mode (SCC) [1]. In [2], SCC-128 (SCC which uses AES with 128-bit key) was broken using 5 attacks, where the authors used an active attack model (where the attacker can force the disk encryption application to re-encrypt a sector for her), the complexity of these attacks are at most 2 cipher executions. In th...

Status of this Memo This document specifies an Internet standards track protocol for the Internet community, and requests discussion and suggestions for improvements. Please refer to the current edition of the "Internet Official Protocol Standards" (STD 1) for the standardization state and status of this protocol. Distribution of this memo is unlimited. The IP, UDP, and TCP MIB modules currentl...