0164-1212/$ see front matter 2009 Elsevier Inc. A doi:10.1016/j.jss.2009.03.014 * Corresponding author. Tel.: +1 817 272 1332; fax E-mail addresses: [email protected] (S. Ferreira), col [email protected] (D. Shunk), [email protected] (G This paper introduces an executable system dynamics simulation model developed to help project managers comprehend the complex impacts related to requirements vol...

BACKGROUND Continuous spinal anesthesia is a very reliable and versatile technique for providing effective anesthesia and analgesia. However, the incidence of possible complications, including postdural puncture headache or neurological impairment, remains controversial. Therefore, the aim of the present retrospective study was to analyze a large number of patients for the incidence of adverse ...

N.M. Wulffraat and MW Heijstek, Department of pediatric rheumatology, UMC Utrecht, The Netherlands In order to develop evidence-based recommendations for vaccination of pediatric patients with auto-immune and/ or auto-inflammatory diseases, a EULAR task force performed a systematic literature review. Available evidence was critically appraised using a customary scoring system for the level of e...

The Matérn family of functions is a widely used covariance kernel in spatial statistics for Gaussian process modeling, which in many instances requires calculation with a covariance matrix. In this paper, we design a fast summation algorithm for the Matérn kernel in order to efficiently perform matrix-vector multiplications. This algorithm is based on the Barnes–Hut tree code framework, and sev...

The nature of the excess near-infrared emission associatedwith themagneticwhite dwarf commonly known as SDSS 1212 is investigated primarily through spectroscopy, and also via photometry. The inferred low-mass secondary in this system has been previously detected by the emission and variation of H , and the 1–2.5 m spectral data presented here are consistent with the presence of a late L or earl...

BACKGROUND Gene-environment interactions are assumed to be involved in the development of depression. OBJECTIVE To determine whether the serotonin receptor 2A (HTR2A) gene moderates the association between childhood maternal nurturance and depressive symptoms in adulthood. DESIGN A 21-year, prospective, longitudinal study with 2 measurements of the independent and dependent variables. SET...

Computational methods, which can be implemented using standard Cox regression software, are given for fitting “exact” pseudolikehood estimates and robust and asymptotic variance estimators from case-cohort data. These methods are based on the computational approach of Therneau and Li (1999) but will be less subject to small sample bias. Further, it is shown how cumulative hazard or survival cur...

1967, p. 21C; F. Schlenk, S. K. Shapiro, and L. W. Parks, International Symp. on Enz. Chem., Tokyo and Kyoto, 1967 (in press.) 11 R. A. McCrorie, M. R. Glasener, C. G. Skinner, and W. Shive, J. Biol. Chem., 211, 489, 1954. 12 W. Shive, Ann. N.Y. Acad. Sci., 52, 1212, 1950. 13 H. R. Alimchandani and A. Sreenivasan, Biochim. et Biophys. Acta, 18, 567, 1955. 14 L. S. Lockingen (in preparation). 15...

The suitability of protein and glucosamine measurements of cell components for biomass estimation of fungi Aspergillus niger S,4, a mangrove isolate, and Aspergillus oryzae NCIM 1212 was evaluated using wheat bran as substrate in solid-state fermentation (SSF). Both direct as well as indirect methods were used. The protein and glucosamine contents and direct weight of the fungi were determined ...

κ-casein is a glycosilated protein belonging to a family of phosphoproteins (αs1,β, αs2,κ) that represents the major protein component in mammalian milk. κ-casein plays an essential role in the case of micelle stabilization, determining the size and the specific biological function. In the present study, we report the characterization of the partial sequence of κ-casein promoter region in the I...