objective(s): there is controversial evidence about the effect of methamphetamine (meth) on spatial memory. we tested the time- dependent effects of meth on spatial short-term (working) and long-term (reference) memory in meth –sensitized and withdrawn rats in the morris water maze. materials and methods: rats were sensitized to meth (2 mg/kg, daily/5 days, sc). rats were trained in water maze ...

BACKGROUND Since most hip fractures are related to osteoporosis, treating accelerated bone loss can be an important strategy to prevent hip fractures. Thiazides have been associated with reduced age-related bone loss by decreasing urinary calcium excretion. OBJECTIVE To examine the association between dose and duration of thiazide diuretic use and the risk for hip fracture and to study the co...

CONTEXT Cytomegalovirus (CMV) infection is associated with adverse clinical outcomes in immunosuppressed persons, but the incidence and association of CMV reactivation with adverse outcomes in critically ill persons lacking evidence of immunosuppression have not been well defined. OBJECTIVE To determine the association of CMV reactivation with intensive care unit (ICU) and hospital length of ...

The purpose of the current study was to determine the optimal treatment duration of high-voltage pulsed galvanic current (HVPC) in treating chronic pressure ulcers. Sixty volunteers suffering from chronic pressure ulcers participated in the study for a treatment period of five weeks. They were divided randomly and equally into four groups (three treatment groups and one control group). Patients...

Introduction: The impact history of the solar system remains controversial. Early investigation of lunar samples, returned by Apollo astronauts, led to the 'Late Heavy Bombardment' (LHB) concept [1,2] which hypothesized a sharp increase in bolide flux centered around ~3.9 Ga. Evidence for this cataclysm was first derived from whole-rock U-Pb and Rb-Sr ages [2] but subsequently more on 40 Ar-39 ...

This follow-up study investigated the effects of low-level lead exposure during prenatal and early postnatal period on learning and memory in rats immediately after exposure has ceased at weaning and later in their adulthood. Male Wistar-derived rats were exposed to lead (as 0.2 % lead acetate solution) through their mothers during pregnancy and lactation until they were weaned. Mothers of cont...

The ability of stress to interfere with the Leydig cell steroidogenesis has been published previously by others and our laboratory, but the intracellular signaling pathways involved in this process have not been identified and described precisely. In this study, we examined the effects of immobilization stress (1 × 120 min, 2 × 120 min within 2 days, and 10 × 120 min within 10 days) on nitric o...

The aim of this study was to evaluate the effects of premating ewe weight and age on ewe reproductive performance, lamb growth and survival in Central Anatolian Merino (CAM) sheep. The trial included 4935 ewes and 5548 lambs from 23 breeder flocks in Eskişehir Province. The live weights (LWs) and ages of the ewes were recorded 1 week before the mating season. The number of lambs born, fertility...