BACKGROUND 'Vrikshayurveda', an ancient science of plant life described by Surapala, has clearly outlined a systematized agricultural practice that insisted on the use of Kunapa jala (KJ) and Pancha gavya (PG) to enhance the yield and quality of plants. OBJECTIVE An experiment was conducted to evaluate the effect of KJ and PG on growth, physiological, biochemical, quality attributes and yield...

PURPOSE Endothelial dysfunction (ED) is a pivotal phenomenon in the development of cardiovascular disease (CVD) in patients receiving hemodialysis (HD). Indoxyl sulfate (IS) is a known uremic toxin that induces ED in patients with chronic kidney disease. The aim of this study was to investigate whether AST-120, an absorbent of IS, improves microvascular or macrovascular ED in HD patients. MAT...

I n t e r v e n t i o n 70 patients each were allocated to 4 treatments: 1) a 10-day course of once-daily levofloxacin, 500 mg; twice-daily amoxicillin, 1 g; twice-daily rabeprazole, 20 mg (LAR); 2) a 10-day course of once-daily levofloxacin, 500 mg; twice-daily tinidazole, 500 mg; and twice-daily rabeprazole, 20 mg (LTR); 3) a 7-day course of 4 times daily tetracycline, 500 mg; 3 times daily m...

chest pain group. 3) Effective treatment: The efficacy of three standard antianginal drugs on silent myocardial ischemia was studied in 43 patients with EA using Holter monitoring. Antianginal drugs used were long-acting isosorbide dinitrate 40-80 mg/day for nitrates (17 patients), diltiazem 90-180 mg/day for calcium antagonists (13 patients), propranolol 30-60 mg/day or metoprolol 60-120 mg/da...

Goniothalamin was evaluated for its anti-malaria activity in-vivo, using the 4-Day Suppressive Test (Peters & Robinson, 1975). The test were carried out against two strains of rodent malaria parasites, the sensitive strain P. berghei ANKA (MRA 311) strain and the resistant strain P. yoelii (MRA 312). An Initial screening was carried out using a single dose of 10 mg/kg body weight administered s...

Importance Lower systolic blood pressure (SBP) levels are associated with poor outcomes in patients with heart failure. Less is known about this association in heart failure with preserved ejection fraction (HFpEF). Objective To determine the associations of SBP levels with mortality and other outcomes in HFpEF. Design, Setting, and Participants A propensity score-matched observational stud...

We described the first results of a quantitative ultra performance liquid chromatography-tandem mass spectrometry method for a novel antimicrobial peptide (phylloseptin, PSN-1). Chromatographic separation was accomplished on a Waters bridged ethyl hybrid (BEH) C18 (50 mm×2.1 mm, 1.7 μm) column with acetonitrile-water (25:75, v/v) as isocratic mobile phase. Mass spectrometry detection was perfor...

1. Captopril given for 5 days caused a fall in blood pressure in normotensive subjects. The percentage fall in mean supine pressure was greatest on a low sodium diet (10 mmol/day), 19.6%, least on a high sodium diet (350 mmol/day), 11%, and in between on a normal sodium diet (120 mmol/day), 16.5%. 2. Captopril caused a marked fall in plasma aldosterone in normal subjects on all three sodium int...

OBJECTIVE To describe the design, methods, and challenges encountered during a randomized clinical trial aimed to promote water intake for reducing risks of metabolic syndrome in Mexican women. MATERIALS AND METHODS In a randomized clinical trial in Cuernavaca, Mexico, overweight and obese (body mass index [BMI] ≥ 25 < 39) women, 18 - < 45 years old with an intake of sugar-sweetened beverages...

BACKGROUND This study identifies the percentage of opioids prescribed for compensated workplace conditions in Manitoba, Canada and whether Workers Compensation Board (WCB) status is associated with higher prescription opioid doses. METHODS Opioid prescriptions for WCB recipients were linked with databases housed at the Manitoba Center for Health Policy. Duration of continuous opioid prescript...