A single-crystal sheet of graphene is synthesized on the low-symmetry substrate Ir(110) by thermal decomposition C$_2$H$_4$ at 1500 K. Using scanning tunneling microscopy, low-energy electron diffraction, angle-resolved photoemission spectroscopy, and ab initio density functional theory structure electronic properties adsorbed its moir\'e with are uncovered. The layer forms a wave pattern nm le...