PURPOSE To compare the effectiveness of immunization with "naked" DNA corresponding to the genes encoding five HSV-1 glycoproteins, gB, gC, gD, gE, and gI (5gP DNA), with immunization with the five glycoproteins (5gP protein). Also, to compare immunization of 5gP protein in Montanide ISA 720 (SEPPIC, Paris, France), an adjuvant recently approved for use in humans, with immunization of 5gP prote...

conclusions therefore the non-infectious dlps were became infectious if introduced into the cytoplasm of permissive and cancerous cells, without passing attachment and entry process. results we attempt to avoid the attachment and entry of the rotavirus by using lipofectamine to mediate the delivery of viral particles directly into the cytoplasm. dlp was endocytosed into the cytoplasm following ...

background and aim: toothbrushes cannot reach all interdental areas. interdental cleaning is an important part of oral hygiene care. the purpose of this study was to compare the supragingival plaque removal efficacy of an interdental cleaning power device (aquajet) and dental floss. materials and methods: thirty subjects were enrolled in this single-blind, split mouth clinical trial. all the su...

When I hear the words of Jesus in the 11th chapter of Matthew, I am reminded also of similar words found at the Statue of Liberty. They are the words of the poem, “The New Colossus,” written by Emma Lazarus in 1883, and they are engraved on a bronze plaque on the inside of the lower level of the pedestal of the Statue of Liberty: Not like the brazen giant of Greek fame, With conquering limbs as...

results males (8,593 patients) were more likely to have eye trauma than females (1,262). the mean age for the outpatient cases was 20.3 ± 16.39 years and for the inpatient cases it was 22.7 ± 18.95 years. the workplace was the most common site for trauma and the cornea was the most reported anatomically injured site. for those patients who had not used safety and protection equipment, 93.1% wer...

purpose: dry eye syndrome is a multifactorial disorder of the tear film and ocular surface that results in eye discomfort, visual disturbance, and often ocular surface damage. studies suggest that the prevalence of clinically diagnosed dry eye syndrome (des) is 0.4%. to 0.5%, which is highest among women and the elderly. the burden of des can be substantial, affecting visual function, daily act...

Prion diseases, also known as the transmissible spongiform encephalopathies (TSEs), are a group of slowly developing neurodegenerations occurring in human and animals. Prion diseases can be transferred between animals, humans, from humans to animals, and from animals to humans. As a result, the central nervous system is attacked, resulting in microglia activation, astrocytosis, prion plaque dep...

AIMS CF101 demonstrated a marked anti-inflammatory effect in Phase 2 studies conducted in patients with rheumatoid arthritis and dry eye syndrome. The aim of this study was to evaluate the safety and efficacy of CF101 for the treatment of patients with moderate to severe plaque-type psoriasis. MATERIALS AND METHODS This was a phase 2, multicentre, randomized, double-blind, dose-ranging, place...