Background: Sohan is a traditional Iranian confectionery product prepared mainly by mixing and cooking of wheat flour, sugar, malt, oil, natural flavoring additives and coloring materials. Regarding to high consumption and popularity of Sohan as well as importance of its safety and hygienic status, we investigated microbial and chemical profiles of Sohan in retailers throughout Qom province of ...

MBX-102/JNJ-39659100 (MBX-102) is a selective, partial PPAR-γ agonist that lowers glucose in the absence of some of the side effects, such as weight gain and edema, that are observed with the TZDs. Interestingly MBX-102 also displays pronounced triglyceride lowering in preclinical rodent models and in humans. Although in vitro reporter gene studies indicated that MBX-102 acid is a highly select...

The United States, despite its affluence, faces a number of daunting policy challenges. We rank last among 16 wealthy peers in life expectancy, infant mortality, and obesity, and have taken very little action on climate change, despite the extremity of the threat it poses not only to future generations but even those alive today. Complicating matters is that the causes of these policy problems ...

This tutorial paper summarizes the motivations, concepts and techniques of finite-set statistics (FISST), a systemlevel, “top-down,” direct generalization of ordinary single-sensor, single-target engineering statistics to the realm of multisensor, multitarget detection and tracking. Finite-set statistics provides powerful new conceptual and computational methods for dealing with multisensor-mul...

background: sohan is a traditional iranian confectionery product prepared mainly by mixing and cooking of wheat flour, sugar, malt, oil, natural flavoring additives and coloring materials. regarding to high consumption and popularity of sohan as well as importance of its safety and hygienic status, we investigated microbial and chemical profiles of sohan in retailers throughout qom province of ...

UNLABELLED Patients with dermatomyositis (DM) or polymyositis (PM) were studied retrospectively. The patients were divided into four groups: definite PM 24, probable PM 19, definite DM 34 and mild-early DM 25 cases. PM patients complained more often proximal muscle weakness [p <0.01]. DM patients complained more arthralgia [p <0.05], dysphagia [p <0.03] and weight loss [p <0.04]. Five patients ...

Coxibs such as celecoxib, rofecoxib and valdecoxib are introduced as selective COX-2 inhibitors to the market. It has been reported that inhibition of COX-2 beside traditional effects of NSAIDs, reduces the risk of colorectal, breast and lung cancers and slow the progress of Alzheimer’s disease. Zarghi et al. reported 8-benzoyl-2-(4-(methylsulfonyl)phenyl)quinoline-4-carboxylic acid (AZGH 102) ...

PURPOSE This phase Ib study evaluated the safety, pharmacokinetics, pharmacodynamics, and antitumor activity of AMG 102, a fully human monoclonal antibody against hepatocyte growth factor/scatter factor (HGF/SF), in combination with bevacizumab or motesanib in patients with advanced solid tumors. EXPERIMENTAL DESIGN Patients with treatment-refractory advanced solid tumors were sequentially en...