background in spite of dozens of clinical trials to establish effective therapeutic and/or preventive vaccine to resolve hcv infection, no real vaccine has been proved to date. genetic vaccines based on replication-defective adenoviruses have proved to elicit strong and long lasting t-cell responses against a number of viral antigens and are even currently being used for vaccine trials in human...

abstract background and purpose:vector-borne diseases such as malaria and leishmaniasis are still a public health problem in iran. one of the effective ways to prevent of these diseases is to improve the vector control program. we carried out this study for assessment managers of school knowledge, attitude and practice regarding vector control programs. materials and methods:a cross-sectional s...

Blinatumomab, the bispecific T cell engager, has been demonstrated as the most successful BsAb to date. Throughout the past decade, vector design has great importance for the expression of monoclonal antibody in Chinese hamster ovary (CHO) cells. It has been indicated that expression plasmids based on the elongation factor-1 alpha (EF-1 alpha) gene and DHFR selection marker can be highly effect...

a plant viral vector engineered from an in vivo infectious clone of zucchini yellow mosaic virus(zymv) was used to express the human interferon-gamma (inf-γ) in planta. the inf-γ gene was in frame inserted between the p1 and hc-pro orfs of the zymv vector. the infectious activity of the vector was approved by rubbing the plasmid on chenopodium quino a and observing local lesions. individual les...

the principle of dimensionality reduction with pca is the representation of the dataset ‘x’in terms of eigenvectors ei ∈ rn  of its covariance matrix. the eigenvectors oriented in the direction with the maximum variance of x in rn carry the most      relevant information of x. these eigenvectors are called principal components [8]. assume that n images in a set are originally represented in mat...