Vitamin K is a group name for K1 (phylloquinone) and K2 (menaquinones). Both forms contribute to the tissue vitamin K status. Following intestinal absorption, the serum transport of these lipophilic compounds to their target tissues takes place via lipoproteins. In previous studies we have found that K1 is preferentially accumulated in the liver, whereas menaquinones have a more widespread dist...

Vitamin K is an essential in human nutrition for the maintenance of normal blood clotting function. It is involved in the synthesis of prothrombin and is directly related to the concentration of the latter in the circulating blood. We have (Kugelmass and Samuel, 1931) advanced the hypothesis of a dietary basis of the formation of clotting constituents, formulated 'clotting' and 'bleeding' diets...

The difference between vitamin K metabolism in the liver and that in the bone of vitamin K-deficient rats was examined. After 17 d administration of vitamin K-deficient food, vitamin K in the liver was almost depleted, and prothrombin time (PT) was prolonged. Serum total osteocalcin level was slightly decreased by vitamin K deficiency, whereas serum undercarboxylated osteocalcin level did not c...

‎Some improvements of Young inequality and its reverse for positive‎ ‎numbers with Kantorovich constant $K(t‎, ‎2)=frac{(1+t)^2}{4t}$‎ ‎are given‎. ‎Using these inequalities some operator inequalities and‎ ‎Hilbert-Schmidt norm versions for matrices are proved‎. ‎In‎ ‎particular‎, ‎it is shown that if $a‎, ‎b$ are positive numbers and‎ ‎$0 leqslant nu leqslant 1,$ then for all integers $ kgeqsl...