J. Akola,1,2,3,* P. Jóvári,4 I. Kaban,5,6 I. Voleská,7 J. Kolář,7 T. Wágner,7 and R. O. Jones2,8 1Department of Physics, Tampere University of Technology, P.O. Box 692, FI-33101 Tampere, Finland 2Peter Grünberg Institut PGI-1 and JARA/HPC, Forschungszentrum Jülich, D-52425 Jülich, Germany 3COMP Centre of Excellence, Department of Applied Physics, Aalto University, FI-00076 Aalto, Finland 4Resea...

S. Strauf 1 , S. M. Ulrich 1 , K. Sebald 1 , P. Michler *,1 , T. Passow 2 , D. Hommel 2 , G. Bacher 3 , and A. Forchel 1 Institute for Solid State Physics, Semiconductor Optics, University of Bremen, P.O. Box 330440, 28334 Bremen, Germany 2 Institute for Solid State Physics, Semiconductor Epitaxy, University of Bremen, P.O. Box 330440, 28334 Bremen, Germany 3 Technical Physics, University of Wü...

F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 aminoacid motif, the F box (so named because cyclin F was one of the first proteins in which this motif was identified) [1]. Some F-box proteins have been shown to be critical for the controlled degradation of cellular regulatory proteins [2] [3]. In fact, F-box proteins are one of the four subuni...

The nucleotide-binding domain and leucine-rich repeats containing proteins (NLRs) serve as immune receptors in both plants and animals. Overaccumulation of NLRs often leads to autoimmune responses, suggesting that the levels of these immune receptors must be tightly controlled. However, the mechanism by which NLR protein levels are regulated is unknown. Here we report that the F-box protein CPR...

V. K. Lazarov,1 R. Plass,1,* H-C. Poon,1 D. K. Saldin,1 M. Weinert,1 S. A. Chambers,2 and M. Gajdardziska-Josifovska1,† 1Department of Physics and Laboratory for Surface Studies, University of Wisconsin Milwaukee, P. O. Box 413, Milwaukee, Wisconsin 53201, USA 2Fundamental Science Directorate, Pacific Northwest National Laboratory, P. O. Box 999, Richland, Washington 99352, USA sReceived 20 Jul...

Selective protein degradation is a key regulator of neuronal development and synaptogenesis. Complexes that target proteins for degradation often contain F-box proteins. Here we characterize MEC-15, an F-box protein with WD repeats, which is required for the development and function of Caenorhabditis elegans touch receptor neurons (TRNs). Mutations in mec-15 produce defects in TRN touch sensiti...

Haloferax volcanii pre-tRNA(Trp) processing requires box C/D ribonucleoprotein (RNP)-guided 2'-O-methylation of nucleotides C34 and U39 followed by intron excision. Positioning of the box C/D guide RNA within the intron of this pre-tRNA led to the assumption that nucleotide methylation is guided by the cis-positioned box C/D RNPs. We have now investigated the mechanism of 2'-O-methylation for t...

1 Carl v. Ossietzky Universität, Department of Computer Science, P.O. Box 2503, D-26111 Oldenburg, Germany {Martin.Fraenzle|von.Karger}@Informatik.Uni-Oldenburg.DE 2 Christian-Albrechts-Universität Kiel, Department of Computer Science, Preußerstr. 1–9, D-24105 Kiel, Germany [email protected] 3 University of Dortmund, Department of Computer Science, FB 4, LS 5, Baroper Str. 301, D-44221 ...

We propose a new complexity measure for movement of objects, the smoothed motion complexity. Many applications are based on algorithms dealing with moving objects, but usually data of moving objects is inherently noisy due to measurement errors. Smoothed motion complexity considers this imprecise information and uses smoothed analysis [13] to model noisy data. The input is object to slight rand...