Background: Circulating cell-free DNA (cfDNA) is a novel type of biomarker with broad utility in diagnostic medicine, based on the release fragments from dying cells to circulation. We developed an approach for identifying tissue origins cfDNA, using cell-type-specific methylation patterns, massive reference atlas genome-wide methylomes multiple human tissues and cell types. Cancer inflicts dam...

metalloporphirins; cu(tpp), mn(tpp)cl, co(tpp), fe(tpp)cl, zn(tpp) and mn(obp)cl catalyze region and chemoselective silylation of hydroxyl groups with hmds. fe(tpp)cl is the most effective catalyst and silylation occurs immediately in its presence at room temperature.

to study the existence of clostridium septicum as probable agent associated with currently occurrence of black quarter in urmia area, sheep-dung samples were collected. the bacteriological examinations on suspicious gram positive anaerobic spore-bearing bacilli which are in clostridia genus include isolation and biochemical identification were performed. the results showed 28 different types of...