OBJECTIVES To investigate the prognostic value of the neurocognitive status measured by screening instruments, the Montreal Cognitive Assessment (MoCA) and Mini-Mental State Examination (MMSE), individually and in combination with the stroke severity scale, the National Institute of Health Stroke Scale (NIHSS), obtained at the subacute stroke phase or the baseline (≤2 weeks), for functional out...

GNPKVKAH Here we discuss standard ways of assigning a score to each amino acid pair, i.e., to each possible column of a gap-free pairwise protein alignment. Examples of such scoring matrices include the PAM30, PAM70, BLOSUM80, BLOSUM62 and BLOSUM45 matrices that are available on NCBI’s blastp server. Such scores are appropriate for comparing two sequences about which we have no other informatio...

In the ranking of the teaching effectiveness of staff members through their student feedback scores, there can be a problem if it is perceived to be more difficult to obtain high scores in some courses than others. The result would be, therefore, that staff taking ‘difficult’ courses are disadvantaged. For example, it is often claimed that GEM and courses at the 1000 level are more difficult to...

GNPKVKAH Here we discuss standard ways of assigning a score to each amino acid pair, i.e., to each possible column of a gap-free pairwise protein alignment. Examples of such scoring matrices include the PAM30, PAM70, BLOSUM80, BLOSUM62 and BLOSUM45 matrices that are available on NCBI’s blastp server. Such scores are appropriate for comparing two sequences about which we have no other informatio...

The popularity of matching techniques has increased considerably during the last decades. They are mainly used for matching treatment and control units in order to estimate causal treatment effects from observational studies or for integrating two or more data sets that share a common subset of covariates. In focusing on causal inference with observational studies, we discuss multivariate match...

After the sequencing of the complete genomes of several higher organisms, molecular biologists face new challenges in understanding the regulatory mechanisms which control the expression of protein coding genes. The expression of a gene into a functional product is a fairly complex process consisting of several steps, with each step underlying some regulatory mechanism. The first major step in ...

Publishers of sheet music are generally reluctant in distributing their content via the Internet. Although online sheet music distribution’s advantages are numerous the potential risk of Intellectual Property Rights (IPR) infringement, e.g. illegal online distributions, disables any innovation propensity. While active protection techniques only deter external risk factors, additional technology...

The propensity score is the conditional probability of exposure to a treatment given observed covariates. In a cohort study, matching or stratifying treated and control subjects on a single variable, the propensity score, tends to balance all of the observed covariates; however, unlike random assignment of treatments, the propensity score may not also balance unobserved covariates. The authors ...