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Artistic representations of the cosmic contraction and expansion phases branch-cut universe evolution scenarios. On left figure, evolves from negative to positive values imaginary cosmological time ti, circumventing continuously branch-cut; no primordial singularity occurs, only branch points. right point disappear after “realisation” by means a Wick rotation, which is replaced here real contin...
STUDY OBJECTIVES To identify rare allelic variants and HLA alleles in narcolepsy patients with hypocretin (orexin, HCRT) deficiency but lacking DQB1*06:02. SETTINGS China (Peking University People's Hospital), Czech Republic (Charles University), Denmark (Golstrup Hospital), Italy (University of Bologna), Korea (Catholic University), and USA (Stanford University). DESIGN CSF hypocretin-1, D...
Correspondência: Neusa Forti • InCor Av. Dr. Enéas Carvalho de Aguiar, 44 – 05403-904 – São Paulo, SP E-mail: [email protected] Artigo recebido em 13/02/06; artigo revisado recebido em 10/05/06; aceito em 22/06/06. Concentrações sanguíneas altas de lipoproteínas de baixa densidade (LDL) e baixas de lipoproteínas de alta densidade (HDL) constituem fatores primordiais para o desenvolvimento de ...
This study aims to investigate associations between observed clinical parameters and known genetic risk factors of psoriasis in a well-defined prospective cohort of paediatric patients with plaque psoriasis (n = 151). Significant associations were found for paediatric-onset psoriasis with ERAP1 (p = 0.002), IL23R (p = 0.01), LCE3C_LCE3B-del (p = 0.00049) and HLA-C*06 (p = 3.15 × 10(-30)). Psori...
Cytomegalovirus (CMV) and other viruses within the herpes group have recently been shown to induce Fc receptors in infected monolayers. We have examined the possibility that such receptors might facilitate the adherence of antibody-coated bacteria to CMV-infected cells. To do this, we infected confluent human embryonic lung (HEL) cell monolayers with CMV (strain AD 169) and then used a double r...
Recibido: 06-06-12 Aprobado: 13-06-12 Figura 1. Actividades desarrolladas en áreas rurales y periurbanas de la ciudad de Iquitos. A) Descarga de madera transportada en botes rústicos (peque-peque); B) Casas flotantes a orillas de los ríos. La leptospirosis es una enfermedad zoonótica de importancia global causada por especies patógenas de Leptospira sp. Se presenta en áreas rurales y urbanas, p...
Echinacea has been in the news lately, due to a series of studies that found it to be ineffective in protecting against respiratory tract infections such as coughs and colds (Grimm & Muller ’99, Barrett et al ’02, Kreutzfeld ’06). These were all randomised, double blind trials with reasonable numbers of trial subjects, so they cannot be lightly dismissed. In addition to these negative findings,...
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