The majority of viral infections can be self-limited in normal populations, with no requirement for medical intervention. However, the same viruses cause severe diseases patients compromised immunity due to single-gene diseases, AIDS, hematologic malignancies, or those receiving immunosuppressive drugs following organ transplant. Occasionally, these immunocompromised harbor more than one infect...

We present Goddard High Resolution Spectrograph and ORFEUS-II measurements of Si IV, C IV, N V, and O VI absorption in the interstellar medium of the Galactic disk and halo toward the nucleus of the Seyfert galaxy ESO141-055. The high ionization absorption is strong, with line strengths consistent with the spectral signature expected for hot (T ∼> 10 5 K) collisionally ionized gas in either a “...

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The Signal Transducer and Activator of Transcription 3 (STAT3) oncogene is a master regulator of many human cancers, and a well-recognized target for therapeutic intervention. A well known STAT3 inhibitor, S3I-201 (NSC 74859), is hypothesized to block STAT3 function in cancer cells by binding the STAT3 SH2 domain and disrupt STAT3 protein complexation events. In this study, liquid chromatograph...

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Sixty five urine samples of patients suffering from bacteriuria were studied to determine the frequency of occurrence of Escherichia coli (E. coli) serotypes as a causative organism. The later was detected in 100 percent samples. The "OK" antigenic groups encountered were: 0111:K58 (52 strains); 055:K59 (7 strains); 0119:K69 (3 strains); 0128 :K67 (2 strains) and 020a 020c:L61 (1 strain). Colon...

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