Background: Efgartigimod is a human IgG1 antibody Fc-fragment that reduces IgG levels through FcRn blockade. A key efficacy indicator in the treatment of autoantibody-mediated generalized myasthenia gravis (gMG) improvement MG-ADL score. Methods: The ADAPT phase 3 trial evaluated safety and efgartigimod patients with gMG, including reaching maintaining minimal symptom expression (MSE; defined a...

Case studies are becoming an increasingly popular research method. However the usual justification for their use is that they provide a rich picture of a particular situation. While this is certainly true there is a problem in linking the findings to theory. This is particularly true for single case research. However the philosophical position of Critical Realism can supply just such a justific...

Abstract Accreting X-ray pulsars (XRPs) undergo luminous outbursts during which the spectral and timing behavior of neutron star can be studied in detail. We analyze a NuSTAR observation XRP XTE J1858+034 its outburst 2019. The spectrum is fit with phenomenological, semiempirical, physical model. A candidate cyclotron line found at 48 keV, implying magnetic field 5.4 × 10 12 G site emission. Th...