objective(s): the wide scale use of zinc oxide nanoparticles (zno nps) in the consumer market world makes human beings more prone to the exposure to zno nanoparticles and its adverse effects. therefore, the aim of the present study is to assess renal toxicity potential of zno and polyethylene glycol coated zno nanoparticles in rat.materials and methods: co-precipitation chemical method was used...

GR99060 and GR99062 are representatives of a series of 1,2,4-triazino[5,6-b]indole compounds. This series possessed broad-spectrum antifungal activity in vitro. The MIC ranges of the two compounds were as follows: 0.25 to 4 micrograms/ml for Candida albicans, 0.25 to 16 micrograms/ml for Candida sp., 1 to 8 micrograms/ml for Aspergillus spp., and 0.25 to 16 micrograms/ml for Cryptococcus neofor...

background: the use of nanotechnology has led to rapid growth in various areas. thus, health and safety issues of nanoparticles (nps) should be promptly addressed. manganese oxide (mno2) nanoparticles (nps) are typically used for biomedical and industrial applications. however, characterizing the potential human health effects of mno2 nps is required before fully exploiting these materials. the...

By using a 1-butylpyridinium hexafluorophosphate based carbon ionic liquid electrode (CILE) as the working electrode, graphene (GR) nanosheets and silver nanoparticles (Ag NPs) were step by step electrodeposited on the surface of the CILE with potentiostatic method. The fabricated Ag/GR/CILE was used as a new platform for protein electrochemistry and hemoglobin (Hb) was immobilized on its surfa...

OBJECTIVES Dexamethasone (Dex) causes neurodegeneration in developing brain. Insulin-like growth factor-I (IGF-I) and -II (IGF-II) are potent neurotrophic and differentiation factors and play key roles in the regulation of growth and development of CNS. Current project evaluated the effects of Dex on IGF-I and -II in developing rat brains. MATERIAL AND METHODS Sprague-Dawley rat pups in each ...

Based on the extensive application of Peganum harmala (P.h) seeds in the Asian traditional medicine, we tried to investigate its possible anxiety effect. Method: The effect of P.h. extract inhalation was evaluated in adult male rats using elevated plus-maze apparatus. The humidity of prepared ethanol extract was 37%. Animals in different groups (n=6) received 2, 4, 6, 12 or 18 gr/ml doses of...

Saponin-based adjuvants are widely used to enhance humoral and cellular immune responses towards vaccine antigens, although it is not yet completely known how they mediate their stimulatory effects. The aim of this study was to elucidate the mechanism of action of adjuvant Matrix-M™ without antigen and Alum was used as reference adjuvant. Adjuvant Matrix-M™ is comprised of 40 nm nanoparticles c...

The following figures may be of some interest and value towards settling the question whether jail dysentery is mainly of the amoebic or bacillary type. They were collected in Sylhet jail which, like many of the other jails of Bengal and Assam, regularly has a high admission rate for dysentery. It is a large district jail with a population of between 600 and 700. Facilities for bacteriological ...