OBJECTIVE Pregnancy-induced hypertension/preeclampsia (PIH) and fetal growth restriction (FGR) share a common placental origin. The pathologic classification that divides placental lesions to maternal or fetal origin was compared between these disorders. STUDY DESIGN Placentas from pregnancies that were complicated by PIH, normotensive FGR, or by both (combined) were analyzed, and lesions wer...

We study identical mass black hole binaries with spins perpendicular to the binary’s orbital plane. These binaries have individual spins ranging from s=m2 0:90 to 0.90, (s1 s2 in all cases) which is near the limit possible with standard Bowen-York puncture initial data. The extreme cases correspond to the largest initial spin simulations to date. Our results expand the parameter space covered b...

The Centre for the AIDS Programme of Research in South Africa 004 (CAPRISA 004) study demonstrated that vaginally applied tenofovir gel is a promising intervention for protecting women from sexually acquiring human immunodeficiency virus (HIV). However, the potential for emergence of tenofovir resistance remains a concern in women who seroconvert while using the gel despite the lack of plasma v...

Herein we present the largest retrospective case-control series of deep sedation in patients with Rett syndrome, including discussion of the unique aspects of Rett syndrome that make these patients at high risk for sedation. Twenty-one patients with Rett syndrome and 21 control patients who received propofol for deep sedation to facilitate lumbar puncture were compared. Patients with Rett syndr...

BACKGROUND Use of antiretroviral-based microbicides for HIV-1 prophylaxis could introduce a transmission barrier that inadvertently facilitates the selection of fitter viral variants among incident infections. To investigate this, we assessed the in vitro function of gag-protease and nef sequences from participants who acquired HIV-1 during the CAPRISA 004 1% tenofovir microbicide gel trial. ...

Cellular immunity was investigated in 43 patients with multiple myeloma (MM) by assessing ,HTdR uptake induced by monocyte-dependent [CD3 monoclonal antibodies (MoAbs), phytohemagglutinin (PHA)] and monocyte-independent (CD2 MoAbs, ionomycin + phorbolester) stimulations. The former were evaluated in peripheral blood mononuclear cells (PBMNC) and purified T cells; the latter were evaluated in pu...

higher in patients with obstructive MGD than in control subjects (P .001, P=.004, P=.001, P .001, P=.001, and P .001, respectively). Both the upper and lower tarsal conjunctival temperatures had a significant negative correlation with the ocular symptom score (R= 0.7325, P .001; R= 0.6356, P .001, respectively), eyelid margin score (R= 0.6126, P .001; R= 0.4707, P=.004, respectively), superfici...

Pawan Kumar Singh1*, Alok Pandey2 and Rajiv Bhatt3 Author Affiliations 1School of Humanities Social Sciences Thapar Institute Engineering Technology, India 2Centre for the Integrated Rural Development, Banaras Hindu University, 3Department Economics, Received: March 24, 2021| Published: April 06, 2021 Corresponding author: Singh, Assistant Professor, School Sciences, Patiala, Punjab-147 004, DO...

Purpose: The complexity of sarcoma has led to the need for patient selection via in vivo biomarkers. Tumor endothelial marker-1 (TEM-1) is a cell surface marker expressed by the tumor microenvironment. Currently MORAb-004 (Ontuxizumab), an anti-TEM-1 humanized monoclonal antibody, is in sarcoma clinical trials. Development of positron emission tomography (PET) for in vivo TEM-1 expression may a...