BACKGROUND Admixture mapping of lipids was followed-up by family-based association analysis to identify variants for cardiovascular disease in African Americans. METHODS AND RESULTS The present study conducted admixture mapping analysis for total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and triglycerides. The analysis was performed in 1905 unrela...

Bone strength is influenced by many properties intrinsic to bone, including its mass, geometry, and mineralization. To further advance our understanding of the genetic basis of bone-strength-related traits, we used a large (n = 815), moderately (G(4) ) advanced intercross line (AIL) of mice derived from a high-runner selection line (HR) and the C57BL/6J inbred strain. In total, 16 quantitative ...

BACKGROUND The aim was to predict breeding values of non-phenotyped individuals based on a dataset prepared for the 13th QTL-MAS Workshop in Wageningen. METHODS Genetic co-variance matrices between animals were estimated with three methods: one using pedigree information only and two based on SNP markers from the first chromosome. Quadratic regression of breeding values, estimated separately ...

the objective of this study was to evaluate the potential gain in accuracy of predictions by imputing genotypes from a low-density marker panel (6640 marker with 10 replicates) to a medium-density marker panel in a simulated population of jersey cattle using fimpute software and also to evaluate the reliability of genomic estimate of breeding values (gebv) for milk yield (h2=0.40) and fertility...

Examination of bovine pituitary gland transcriptome by strand-specific RNA-seq allows detection of putative single nucleotide polymorphisms (SNPs) within potential candidate genes (CGs) or QTLs regions as well as to understand the genomics variations that contribute to economic trait. Here we report a breed-specific model to successfully perform the detection of SNPs in the pituitary gland of y...

Bread wheat chromosome 3A has been shown to contain genes/QTLs controlling grain yield and other agronomic traits. The objectives of this study were to generate high-density physical and genetic-linkage maps of wheat homoeologous group 3 chromosomes and reveal the physical locations of genes/QTLs controlling yield and its component traits, as well as agronomic traits, to obtain a precise estima...

The objective of this study was to evaluate boron tolerance wheat genotypes using mature embryo culture. analysis involved 79 recombinant inbred lines the International Triticeae Mapping Initiative (ITMI) population and three Serbian varieties with known (B) (Pobeda - sensitive S, Balerina-medium tolerant MT, Nevesinjka T). evaluation performed on a modified MS medium which 15 mM boric acid add...

Phosphorus is the one of most important macro-elements for growth, development as well productivity plants. However, overuse fertilizer negatively affects soil and water quality, run-out natural phosphates (Pi). Therefore, it necessary to study on Pi cycle find out way use efficiently rice other crops. In this work, genome wide association studies (GWAS) was used investigate diversity in uptaki...