The cellular enamel organ and the cell-free organic matrix of developing enamel of female rats injected intravascularly with [3H]serine and [3H]proline were extracted in a number of solvents and examined by sodium dodecyl sulphate/polyacrylamide-gel electrophoresis and h.p.l.c. in 6M-guanidinium chloride at intervals varying from 5 min to 1 week after injection. Three major species soluble in N...

The final purification of the three-fraction enzyme complex mycobacillin synthetase was done by hydroxyapatite column chromatography and sucrose-density-gradient centrifugation; each of the fractions obtained migrates as a single component in SDS/polyacrylamide-gel electrophoresis and gel electrofocusing. The Mr of the enzyme fractions A, B and C by gel filtration is 260 000, 190 000 and 105 00...

We have shown previously, by fluorescent antibody staining, that desmosomal antigens are widely distributed in the tissues of vertebrate animals. Furthermore, we have demonstrated mutual desmosome formation between cells derived from man, cow, dog, chicken and frog. In this paper we have studied the components of desmosomes in a tissue or a cell line from each of these animals by immunoblotting...

Estimation of pathogen-specific causes of child diarrhea deaths is needed to guide vaccine development and other prevention strategies. We did a systematic review of articles published between 1990 and 2011 reporting at least one of 13 pathogens in children <5 years of age hospitalized with diarrhea. We included 2011 rotavirus data from the Rotavirus Surveillance Network coordinated by WHO. We ...

OBJECTIVES  To estimate the potential impact of universal screening for primary prevention of cardiovascular disease (National Health Service Health Checks) on disease burden and socioeconomic inequalities in health in England, and to compare universal screening with alternative feasible strategies. DESIGN  Microsimulation study of a close-to-reality synthetic population. Five scenarios were ...

where g1 is the electrostrictive coupling constant, τ is the acoustic phonon lifetime, and Ap, As are the complex amplitudes of counterpropagating pump and signal waves respectively. It can be observed that this equation represents convolution of the counterpropagating optical waves. For pump and probe modulated with a pseudo-random bit sequence (PRBS), this convolution leads to a triangular sh...

If a and b are positive integers with a ≤ b and a ≡ a mod b, then the set Ma,b = {x ∈ N : x ≡ a mod b or x = 1} is a multiplicative monoid known as an arithmetical congruence monoid (or ACM). For any monoidM with unitsM× and any x ∈ M \M× we say that t ∈ N is a factorization length of x if and only if there exist irreducible elements y1, . . . , yt ofM and x = y1 · · · yt. Let L(x) = {t1, . . ....

Component failure in large-scale IT installations is becoming an ever larger problem as the number of components in a single cluster approaches a million. In this paper, we present and analyze field-gathered disk replacement data from a number of large production systems, including high-performance computing sites and internet services sites. About 100,000 disks are covered by this data, some f...

Brief digestion of ox neurofilaments with trypsin liberates fragments that are soluble and have molecular weights ranging from 164 000 to 97 000. Peptide fingerprinting indicates that these regions, termed the tryptic head-regions, arise from the 205 000- and 158 000-mol.wt. components of the triplet. The remains of the parent polypeptides sediment with normal filaments and have been termed tai...