BACKGROUND Leishmania is a mammalian parasite affecting over 12 million individuals worldwide. Current treatments are expensive, cause severe side effects, and emerging drug resistance has been reported. Vaccination is the most cost-effective means to control infectious disease but currently there is no vaccine available against Leishmaniasis. Lactococcus lactis is a non-pathogenic, non-coloniz...

Formamide-insoluble material was isolated from the L-form of Streptococcus faecium strain F24, but this material was not murein.

There has been considerable controversy about the action of heparin on mitosis. Early workers in tissue culture routinely used heparizined plasma without apparent inhibition of growth (2). Later, however, several investigators reported that hepa rin inhibited mitosis either in vitro or in vivo (1, 4, 5, 15), although others found it was not in hibitory (8, 10, 14). A search is being made in our...

There has been considerable controversy about the action of heparin on mitosis. Early workers in tissue culture routinely used heparizined plasma without apparent inhibition of growth (2). Later, however, several investigators reported that hepa rin inhibited mitosis either in vitro or in vivo (1, 4, 5, 15), although others found it was not in hibitory (8, 10, 14). A search is being made in our...

Administration of L-tryptophan to normal fed rats inhibits hepatic gluconeogenesis at the level of P-enolpyruvate formation but nonetheless causes a paradoxical increase in the assayable specific activity of P-enolpyruvate carboxykinase. Similar results obtain if livers isolated from normal rats are perfused with tryptophan, 3-hydroxyanthranilate or quinolinate. However, we find that no such in...

Abstract. Dewiyanti I, Darmawi D, Muchlisin ZA, Helmi TZ, Arisa II, Rahmiati R, Destri E, Fanisha S. 2022. Characteristic and activity of cellulolytic bacteria isolated from mangrove soil in Northern Coast Aceh Province, Indonesia. Biodiversitas 23: 6587-6599. The as decomposing cellulose is related to the fertility productivity ecosystem, presence enzymes produced can evaluate them. study aims...

Valaciclovir is rapidly and extensively converted to acyclovir. In this study we investigated the potential interaction between oral valaciclovir and Maalox. On each of three occasions 18 healthy volunteers received a single oral dose of 1000 mg valaciclovir, or 30 mL Maalox 65 min after valaciclovir administration, or 30 mL Maalox 30 min before valaciclovir. Acyclovir plasma concentrations and...

Administration of L-tryptophan to normal fed rats inhibits hepatic gluconeogenesis at the level of P-enolpyruvate formation but nonetheless causes a paradoxical increase in the assayable specific activity of P-enolpyruvate carboxykinase. Similar results obtain if livers isolated from normal rats are perfused with tryptophan, 3-hydroxyanthranilate or quinolinate. However, we find that no such in...

Thyroid hormones stimulate aerobic metabolism which may lead to oxidative stress accompanied by damage to various cellular macromolecules, including DNA. Previous comet assay studies have shown that thyroid hormones cause DNA damage due to the creation of reactive oxygen species (ROS). However, cytogenetic studies have been equivocal because although an increase in the sister-chromatid exchange...

In this article, we describe the surprising non-specific reactivity in immunoblots of a rabbit polyclonal antibody (ref. Abcam 86222) expected to recognize the transporter associated with antigen processing like (TAP-L, ABCB9) protein. Although this antibody, according to company documentation, recognizes a band with the expected molecular weight of 84 kDa in HeLa, 293T and mouse NIH3T3 whole-c...