This report describes preclinical and early clinical investigations of the mitoxantrone/paclitaxel combination (NT) for patients with platinum-refractory ovarian cancer. The preclinical activity of NT was studied ex vivo, evaluating native tumor specimens with the ATP tumor chemosensitivity assay. Of 24 tumors tested, 20 (83%) were sensitive to NT, whereas 7 (29%) responded to mitoxantrone and ...

Objective: In this study, we aimed to evaluate the relationship between thiol-disulfide homoeostasis and hemogram parameters in COVID-19 patients.
 Methods: Total thiol(TT), Native thiol(NT), dynamic disulfide status(DDS), DDS/NT, DDS/TT, NT/TT ratio CBC were analyzed 68 patients with positive 31 healthy individuals.
 Results: TT, NT, DD, hemoglobin hematocrit levels higher control gr...

OBJECTIVE Fetal nuchal translucency (NT) thickness is an important marker for prenatal screening; however, studies focusing on the correlation between maternal trace element levels and NT thickness are limited. The aim of this study was to evaluate maternal trace element levels during the first trimester and to investigate the association between maternal trace element levels and fetal NT thick...

AIMS To compare the accuracy of the N-terminal fragment of its pro-hormone (Nt-proBNP) and N-terminal pro-atrial natriuretic peptide (Nt-proANP) in the prediction of the 2 year mortality and to investigate whether additional measurement of Nt-proANP to troponin I (TnI) could improve risk assessment in the subgroups of patients with unstable coronary artery disease (UCAD) and normal Nt-proBNP. ...

BACKGROUND Negative T (NT) wave in electrocardiography (ECG) is one of the important factors in determining short- and long-term outcomes in patients with acute myocardial infarction (MI). In this study, we compared clinical and paraclinical findings in post-MI patients according to presence or absence of NT wave. METHODS A cross-sectional study was conducted on patients with acute ST elevati...

Neurotensin (NT) is a neuropeptide identical in mice and humans that is produced and released in many CNS regions associated with maternal behavior. NT has been linked to aspects of maternal care and previous studies have indirectly suggested that endogenous NT signaling is altered in the postpartum period. In the present study, we directly examine whether NT and its receptors exhibit altered g...

More and more high available applications are implemented on Windows NT. However, the current version of Windows NT (NT4) does not provide some facilities that are needed to implement these fault tolerant applications. In this paper, we describe a set of components collectively named NT-SwiFT (Software Implemented Fault Tolerance) which facilitates building fault-tolerant and highly available a...

Résumé. Suite à la survenue récente de scandales financiers, la synthèse des idées mobilisables en gouvernance d’entreprise semble désormais essentielle si l’on veut sécuriser les investisseurs. Dans cette perspective, le présent projet de recherche consiste à mettre en œuvre un panel d’outils d’analyse de données textuelles (Alceste, Syntex, Tropes-Zoom/Decision Explorer, Wordmapper, Weblex) a...