نتایج جستجو برای: ژن gyrb

تعداد نتایج: 16650  

Journal: :The Journal of antimicrobial chemotherapy 2008
Rocío Enríquez Raquel Abad Celia Salcedo Sonia Pérez Julio A Vázquez

OBJECTIVES To assess the ciprofloxacin resistance of Neisseria meningitidis isolated from 1999 through 2006 in Spain, susceptibility testing was conducted on 5300 isolates. METHODS Ten isolates showed MICs of ciprofloxacin ranging between 0.06 and 0.25 mg/L, and they were characterized by analysis for mutations within the quinolone resistance determining regions (QRDRs) in the gyrA, gyrB, par...

Journal: :Antimicrobial agents and chemotherapy 1999
Y Onodera K Sato

The genes encoding the DNA gyrase A and B subunits of Bacteroides fragilis were cloned and sequenced. The gyrA and gyrB genes code for proteins of 845 and 653 amino acids, respectively. These proteins were expressed in Escherichia coli, and the combination of GyrA and GyrB exhibited ATP-dependent supercoiling activity. To analyze the role of DNA gyrase in quinolone resistance of B. fragilis, we...

2018
Amal Oudghiri Hind Karimi Fouad Chetioui Fathiah Zakham Jamal Eddine Bourkadi My Driss Elmessaoudi Amin Laglaoui Imane Chaoui Mohammed El Mzibri

BACKGROUND The emergence of extensively drug-resistant tuberculosis (XDR-TB) has raised public health concern for global TB control. Although multi drug-resistant tuberculosis (MDR- TB) prevalence and associated genetic mutations in Morocco are well documented, scarce information on XDR TB is available. Hence, the evaluation of pre-XDR and XDR prevalence, as well as the mutation status of gyrA,...

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