نتایج جستجو برای: پروتئین cota

تعداد نتایج: 18103  

Journal: :Biochemical Society transactions 2007
E P Melo A T Fernandes P Durão L O Martins

The axial ligand of the catalytic mononuclear T1 copper site (Met(502)) of the CotA laccase was replaced by a leucine or phenylalanine residue to increase the redox potential of the enzyme. These mutations led to an increase in the redox potential by approx. 100 mV relative to the wild-type enzyme but the catalytic constant k(cat) in the mutant enzymes was severely compromised. This decrease in...

2015
Rabih S Talhouk Bilal Nasr Mohamed-Bilal Fares Bushra Ajeeb Rana Nahhas Lamis Al Aaraj Salma N Talhouk Tarek H Ghaddar Najat A Saliba

A sesquiterpene lactone 1-β,10-Epoxy-6-hydroxy-1,10H-inunolide (K100) was isolated through "bioassay-guided fractionation" from Cota palaestina subsp. syriaca, an Eastern Mediterranean endemic plant. K100 inhibited endotoxin- (ET-) induced proinflammatory markers: IL-6, MMP-9, and NO in normal mouse mammary SCp2 Cells. Molecular docking in silico suggested that K100, having highly analogous str...

Journal: :Ekonomski Vjesnik 2021

Purpose: In this paper, the volatility of Croatian stock market index CROBEX is investigated using GARCH(1,1) model. Methodology: The novelty provided by paper estimation model three conditional error distributions (normal (Gaussian) distribution, Student’s-distribution with fixed degrees freedom and generalized distribution (GED) parameters). Results: findings obtained in research are line pre...

Journal: :Natural Hazards 2023

In Brazil, research related to the occurrence and prevention of debris flows is incipient when compared extent impacts caused by phenomena. There a need for further studies that consider susceptibility hazard, especially in areas are environmentally socioeconomically vulnerable. This study aimed at assessing debris-flow hazard Rio das Pedras watershed, Cubatão (State São Paulo, Brazil), based o...

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