نتایج جستجو برای: پروبیوتیک abt 10
تعداد نتایج: 1019339 فیلتر نتایج به سال:
باکتوسل نخستین پروبیوتیک مجاز در آبزیان می باشد که در سال 2009 در اتحادیه اروپا به ثبت رسیده است. این پروبیوتیک با ایجاد تغییرات مفید در جمعیت میکروبی روده و تولید اسیدلاکتیک منجر به بهبود رشد، تولید و بازماندگی انواع ماهی و میگو می گردد. بدین جهت تحقیقی جهت مقایسه اثرات سه دز متفاوت پروبیوتیک باکتوسل حاوی باکتری Pediococcus acidilactici بر شاخص های رشد ما...
A classical velocity centrifugation technique was used to study the in vitro uptake of the new ketolide ABT-773 by human polymorphonuclear neutrophils (PMNs) and a myelomonoblastic cell line, PLB-985, which can be differentiated into PMNs under certain culture conditions, compared to that of HMR 3004. ABT-773 was rapidly taken up by PMNs (cellular concentration to extracellular concentration ra...
چکیده در این پژوهش اثر پروبیوتیک باسیلوس سوبتیلیس بر وضعیت اکسیداتیو (پراکسیداسیون لیپیدها و فعالیت آنزیم های سوپراکسید دیسموتاز و کاتالاز) در ماهی قزل آلای رنگین کمان تغذیه شده با جیره ی حاوی پروبیوتیک باسیلوس سوبتیلیس مورد بررسی قرار گرفت. پروبیوتیک باسیلوس سوبتیلیس جیره در 3 سطح 2/0، 4/0 و 6/0 گرم در کیلوگرم به جیره غذایی اضافه گردید و جیره فاقد پروبیوتیک باسیلوس سوبتیلیس برای تغذیه گروه ...
Tumor initiation, progression and resistance to therapies are tightly associated with over-expression of anti-apoptotic proteins Bcl-2, Bcl-x(L), Bcl-w and Mcl-1. ABT-263 (Navitoclax), an orally bio-available small-molecule mimetic of the Bcl-2 homology domain 3, inhibits Bcl-2, Bcl-x(L), and Bcl-w and has shown anti-cancer effects mainly on lymphomas and lymphocytic leukemia. Despite promising...
1-Aminobenzotriazole (ABT) has been extensively used as a nonspecific inhibitor of cytochromes p450 (p450s) in animals for mechanistic studies, and antipyrine (AP) has been used as a probe for hepatic oxidative metabolic capacity determination in vivo. The method of use of ABT has been variable from lab to lab due largely to unknown pharmacokinetics of ABT itself and incomplete information on v...
In vitro activities of ABT-492, ciprofloxacin, levofloxacin, trovafloxacin, moxifloxacin, gatifloxacin, and gemifloxacin were compared. ABT-492 was more potent against quinolone-susceptible and -resistant gram-positive organisms, had activity similar to that of ciprofloxacin against certain members of the family Enterobacteriaceae, and had comparable activity against quinolone-susceptible, nonf...
Targeting tumor-overexpressed EGFR with an antibody-drug conjugate (ADC) is an attractive therapeutic strategy; however, normal tissue expression represents a significant toxicity risk. The anti-EGFR antibody ABT-806 targets a unique tumor-specific epitope and exhibits minimal reactivity to EGFR in normal tissue, suggesting its suitability for the development of an ADC. We describe the binding ...
Docetaxel (DTX) is a useful chemotherapeutic drug for the treatment of hormone-refractory prostate cancer. However, emergence of DTX resistance has been a therapeutic hurdle. In this study, we investigated the effect of combining DTX with Bcl-2 family inhibitors using human prostate cancer cell lines (PC3, LNCaP, and DU145 cells). PC3 cells were less sensitive to DTX than were the other two cel...
Poly(ADP-ribose) polymerase (PARP) senses DNA breaks and facilitates DNA repair via the polyADP-ribosylation of various DNA binding and repair proteins. We explored the mechanism of potentiation of temozolomide cytotoxicity by the PARP inhibitor ABT-888. We showed that cells treated with temozolomide need to be exposed to ABT-888 for at least 17 to 24 hours to achieve maximal cytotoxicity. The ...
The in vitro susceptibilities of 103 Mycoplasma pneumoniae isolates, 14 Mycoplasma hominis isolates, 12 Mycoplasma fermentans isolates, and 24 Ureaplasma species to ABT-773, an investigational ketolide, and seven other agents were determined. For M. pneumoniae, the ABT-773 MIC at which 90% of isolates are inhibited (MIC(90); <or=0.001 microg/ml) was comparable to those of azithromycin, clarithr...
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