This study aimed to investigate the effects of polymorphisms of the flavin-containing mono-oxygenase 3 (FMO3) and flavin-containing mono-oxygenase 6 (FMO6) genes on the pharmacokinetics of sulindac sulfide, the active metabolite of sulindac, in patients with preterm labor. Ten single-nucleotide polymorphisms (SNPs) were genotyped, and plasma sulindac sulfide concentrations were measured at 0, 1...

On a nonstandard two-parametric quantum algebra and its connections with U p,q (gl(2)) and U p,q (gl(1|1)) Abstract. A quantum algebra U p,q (ζ, H, X ±) associated with a nonstandard R-matrix with two deformation parameters(p, q) is studied and, in particular, its universal R-matrix is derived using Reshetikhin's method. Explicit construction of the (p, q)-dependent nonstandard R-matrix is obta...

ITE JOURNAL / FEBRUARY 2002 TOLL FACILITIES CANNOT BE CLASsified under the same pretenses as normal freeway segments or signalized intersections because of the unique characteristics associated with toll plazas being integrated within the system. Therefore, it is difficult to examine the operational conditions and accurately report the benefits of toll facilities to the public in terms they can...

Volume 30, Number 1, January/February 1998 swers into a laptop computer. A revised questionnaire using CAPI was pretested between October and December 1993. About 800 eligible women were selected, and 500 were interviewed. The pretest was an experiment, which compared results for women who received incentives with results for women who did not. Incentives increased response rates, reduced costs...

TAR DNA-binding protein (TDP-43) is a highly conserved and essential DNA- and RNA-binding protein that controls gene expression through RNA processing, in particular, regulation of splicing. Intracellular aggregation of TDP-43 is a hallmark of amyotrophic lateral sclerosis and ubiquitin-positive frontotemporal lobar degeneration. This TDP-43 pathology is also present in other types of neurodege...