We evaluated the BACTEC MGIT 960 system, which is a fully automated, noninvasive system for the growth and detection of mycobacteria with a capacity to incubate and continuously monitor 960 7-ml culture tubes. We studied 3,330 specimens, 2,210 respiratory and 1,120 nonrespiratory specimens, collected from 2,346 patients treated at six sites. Processed specimens were inoculated into the BACTEC M...

The secondary structures of three snake venom cardiotoxins (from Hemachatus hemachatus, Naja naja atra, and Naja naja naja), in aqueous solution and in a lipid-bound form, were investigated by Fourier-transform infrared spectroscopy. The conformation-sensitive protein infrared bands in the amide I region were analyzed using deconvolution and band-fitting procedures. The spectra of the three car...

We evaluated the performance of BACTEC MGIT 960 for automated testing of the susceptibility of 133 strains of Mycobacterium tuberculosis to streptomycin, isoniazid, rifampin, and ethambutol. The BACTEC MGIT 960 results were compared with those obtained with the radiometric BACTEC 460TB system, and when there was disagreement, the method of proportion on agar plates was used as a reference metho...

This work describes a 12b 120MS/s dual-channel SHAfree Nyquist ADC based on a mid-code calibration technique eliminating offset mismatch between channels. The prototype ADC achieves a peak SNDR of 61.1dB and a peak SFDR of 74.7dB for input frequencies up to 60MHz at 120MS/s. Also, the measured DNL and INL are within 0.30LSB and 0.95LSB, respectively. The ADC fabricated in a 0.13 m CMOS process ...

and Applied Analysis 3 Case 1. Suppose that m = 1, by equating the coefficients of Y i (i = 2, 1, 0) on both sides of (11), we have a 󸀠 1 (X) = g (X) a 1 (X) , (12a) a 󸀠 0 (X) = h (X) a 1 (X) + g (X) a 0 (X) , (12b) a 1 (X)(( 2 c − 1 )X 3 + ( w 2 − 2n − (a + cw) 2

C-Glycosyl-(S)- and (R)-alanines 12a and 12b were synthesized from the known beta-C-glycoside 1. The nitrogen function was introduced by aza-Claisen rearrangement of the allylic thiocyanate 7, derived from the corresponding alcohol 6. The absolute configuration of the newly created chiral carbon center (C-3) was assigned by X-ray diffraction analysis of the intermediate 3(S)-isothiocyanato-D-gl...

Lividamine and paromamine were converted into two key intermediate ethylenic aldehydes 10a and 10b. Reductive amination of the two aldehydes yielded the protected sisamine 11a and the three analogs 11b, 12a and 12b. These four derivatives were deprotected to yield the four pseudodisaccharides 1a, 1b, 2a and 2b which were less active in vitro than neamine against Escherichia coli ATCC 9637 and S...