The expression of troponin (Tn) T, a thin-filament regulatory protein, was examined in left ventricular myocardium from normal and from failing adult human hearts. The differences in isoform expression between normal and failing myocardium led us to examine the ontogenic expression of TnT in human striated muscle. Left ventricular samples were obtained from patients with severe heart failure un...

The first generation of troponin T ELISA (TnT 1) can yield false-positive results in patients with severe skeletal muscle injury. Therefore, a cardiac-specific second-generation troponin T ELISA (TnT 2) was developed, in which the cross-reactive antibody 1B10 has been replaced by a high-affinity cardiac-specific antibody M11.7. No cross-reactivity of TnT 2 was observed with purified skeletal mu...

Many microbes reduce the nitro substituents of 2,4,6-trinitrotoluene (TNT), producing aminodinitrotoluenes (ADNTs). These compounds are recalcitrant to further breakdown and are acutely toxic. In a search for organisms capable of metabolizing ADNTs, a bacterial strain was isolated for the ability to use 2-aminobenzoate (anthranilate) as sole C-source. This isolate, Pseudomonas aeruginosa MAO1, ...

Degradation of TNT by bovine rumen fluid, a novel source of anaerobic microbes, was investigated. Whole rumen fluid contents were spiked with TNT and incubated for a 24h time period. Supernatant samples taken at 0, 1, 2, 4, and 24h were analyzed by reverse-phase HPLC with diode array detection. Within 1h, TNT was not detectable and reduction products of TNT including 2-hydroxyl-amino-4,6-dinitr...

Heterogeneous domain adaptation (HDA) addresses the task of associating data not only across dissimilar domains but also described by different types of features. Inspired by the recent advances of neural networks and deep learning, we propose Transfer Neural Trees (TNT) which jointly solves cross-domain feature mapping, adaptation, and classification in a NN-based architecture. As the predicti...

Enterobacter cloacae PB2 was originally isolated on the basis of its ability to utilize nitrate esters, such as pentaerythritol tetranitrate (PETN) and glycerol trinitrate, as the sole nitrogen source for growth. The enzyme responsible is an NADPH-dependent reductase designated PETN reductase. E. cloacae PB2 was found to be capable of slow aerobic growth with 2,4,6-trinitrotoluene (TNT) as the ...

Cell to cell communication is essential for the organization/coordination of multicellular systems and cellular development. Cellular communication is mediated by soluble factors, including growth factors, neurotransmitters, cytokines/chemokines, gap junctions, and the recently described tunneling nanotubes (TNT). TNT are long cytoplasmatic bridges that enable long range directed communication ...

land mines are one of the tragic problems to human security in many countries. among many techniques suggested detecting landmines, plant-based detectors can be used as a reliable tool for unexploded ordnance detection. this study was conducted to determine different concentrations effect of trinitrotoluene (0, 5, 10, 15, 20, 30, 45 and 60 ppm) on germination and early seedling growth of 6 spec...

The production and storage of explosives has resulted in the environmental accumulation of 2,4,6-trinitrotoluene (TNT). The biotransformation products of the nitroaromatic compound TNT and metabolites in mammalian cells in culture and their cytotoxicity are studied. We report after our analysis by reverse phase high performance liquid chromatography (HPLC) that the most prevalent biotransformat...

درطول تاریخ، قرآن با انگیزه‌ واهداف متعددی ترجمه و بازترجمه شده‌است. آغازقرن بیستم وتداوم نگرش علمی محققانه درحوزۀ اسلام شناسی قرن هجدهم نوزدهم میلادی، شرق شناسان دین‌پژوه بمنظورمقابله دیدگاه‌های غرض ورز ترجمه‌های‌غیرعلمی سده های قبل، به بازترجمه‌های‌علمی وکاربردی مبادرت کردند. ازجمله ترجمه‌های شاخص حاضرمی توان هارتموت بوبتسین شناس ودین پژوه آلمانی اشاره کرد که بصورت مستقیم ازاصل عربی زبان . یک...